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评估猫过敏性皮炎评分与猫皮肤病范围和严重程度指数以及特应性猫皮肤水合作用之间的相关性。

Evaluation of the correlation between Scoring Feline Allergic Dermatitis and Feline Extent and Severity Index and skin hydration in atopic cats.

作者信息

Szczepanik Marcin P, Wilkołek Piotr M, Adamek Łukasz R, Zając Marcin, Gołyński Marcin, Sitkowski Wiesław, Taszkun Iwona

机构信息

Subdepartment of Clinical Diagnostics and Veterinary Dermatology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Głęboka 30, 20-612, Lublin, Poland.

Private veterinary practice Bafir, ul. Szpitalna 9a, 41-250, Czeladź, Poland.

出版信息

Vet Dermatol. 2018 Feb;29(1):34-e16. doi: 10.1111/vde.12489. Epub 2017 Sep 13.

DOI:10.1111/vde.12489
PMID:28901591
Abstract

BACKGROUND

Evaluation of the severity of clinical signs of cats with allergic skin diseases has used two scoring systems: Scoring Feline Allergic Dermatitis (SCORFAD) and the Feline Extent and Severity Index (FeDESI). The integrity of the cutaneous barrier can also be evaluated by measuring skin hydration. A correlation between the clinical score and skin hydration has been observed in humans and dogs with atopic dermatitis (AD).

HYPOTHESIS

To demonstrate a correlation between the clinical score and skin hydration of cats affected with presumed AD.

ANIMALS

European short hair cats (n = 18): 11 females and seven males with a confirmed diagnosis of AD.

METHODS

SCORFAD and FeDESI scores were calculated and the measurements of skin hydration were assessed from seven body sites using corneometry. The correlation between the SCORFAD and FeDESI systems and skin hydration of each site, and the average skin hydration was calculated.

RESULTS

There was a positive correlation between the SCORFAD score and skin hydration for the axilla, thorax and forelimb; for FeDESI and axilla and lumbar sites. There was a negative correlation between the FeDESI and skin hydration for the pinna (r = -0.47).

CONCLUSIONS AND CLINICAL IMPORTANCE

Measurements of skin hydration could be a useful tool for the evaluation of allergic cats. There is limited evidence of any useful correlation between clinical scoring systems and measurements of hydration. The pinna may be a suitable region for the assessment of skin barrier function in normal and allergic cats.

摘要

背景

评估患有过敏性皮肤病的猫的临床症状严重程度使用了两种评分系统:猫过敏性皮炎评分(SCORFAD)和猫病损范围及严重程度指数(FeDESI)。皮肤屏障的完整性也可通过测量皮肤水合作用来评估。在患有特应性皮炎(AD)的人和狗中,已观察到临床评分与皮肤水合作用之间存在相关性。

假设

证明疑似患有AD的猫的临床评分与皮肤水合作用之间存在相关性。

动物

欧洲短毛猫(n = 18):11只雌性和7只雄性,确诊为AD。

方法

计算SCORFAD和FeDESI评分,并使用角质层水合测量仪从七个身体部位评估皮肤水合作用的测量值。计算SCORFAD和FeDESI系统与每个部位的皮肤水合作用之间的相关性,以及平均皮肤水合作用。

结果

腋窝、胸部和前肢的SCORFAD评分与皮肤水合作用呈正相关;腋窝和腰部部位的FeDESI评分与皮肤水合作用呈正相关。耳廓的FeDESI评分与皮肤水合作用呈负相关(r = -0.47)。

结论及临床意义

测量皮肤水合作用可能是评估过敏性猫的有用工具。临床评分系统与水合作用测量之间存在任何有用相关性的证据有限。耳廓可能是评估正常和过敏性猫皮肤屏障功能的合适部位。

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引用本文的文献

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Atopic dermatitis in cats and dogs: a difficult disease for animals and owners.猫和狗的特应性皮炎:对动物及其主人来说都是一种棘手的疾病。
Clin Transl Allergy. 2018 Oct 5;8:41. doi: 10.1186/s13601-018-0228-5. eCollection 2018.