Zając Marcin, Szczepanik Marcin P, Wilkołek Piotr M, Adamek Łukasz R, Pomorski Zbigniew J H, Sitkowski Wiesław, Gołyński Marcin
Private Veterinary Clinic, Bafir"ul. Szpitalna 9a 41-250, Czeladź (Zając); Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Głęboka 30, 20-612 Lublin (Szczepanik, Wilkołek, Adamek, Pomorski, Sitkowski); and Sub-Deparment of Internal Diseases of Farm Animals and Horses, University of Life Sciences, Lublin, Poland (Gołyński).
Can J Vet Res. 2015 Apr;79(2):136-40.
Atopic dermatitis is a common allergic skin disease in dogs. The aim of this study was to examine the possibility of a correlation between biophysical skin variables: skin hydration (SH), skin pH, and erythema intensity measured in 10 different body regions and both total Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) and CADESI measured in a given region (CADESI L). The study was conducted using 33 dogs with atopic dermatitis. The assessment of the biophysical variables was done in 10 body regions: the lumbar region, right axillary fossa, right inguinal region, ventral abdominal region, right lateral thorax region, internal surface of the auricle, interdigital region of right forelimb, cheek, bridge of nose, and lateral site of antebrachum. Positive correlations were found between SH and CADESI L for the following regions: the inguinal region (r = 0.73) and the interdigital region (r = 0.82), as well as between total CADESI and SH on digital region (r = 0.52). Also, positive correlations were reported for skin pH and CADESI L in the lumbar region (r = 0.57), the right lateral thorax region (r = 0.40), and the lateral antebrachum (r = 0.35). Positive correlations were found in the interdigital region between erythema intensity and the total CADESI-03 (r = 0.60) as well as the CADESI L (r = 0.7). The results obtained suggest that it may be possible to use skin hydration, pH, and erythema intensity to assess the severity of skin lesion but positive correlation was only found in < 13.3% of possible correlations and usage of these measures in dogs is limited.
特应性皮炎是犬类常见的过敏性皮肤病。本研究的目的是检验生物物理皮肤变量之间的相关性：皮肤水合作用（SH）、皮肤pH值以及在10个不同身体部位测量的红斑强度，与犬特应性皮炎总体范围和严重程度指数（CADESI - 03）以及在特定区域测量的CADESI（CADESI L）之间的相关性。该研究使用了33只患有特应性皮炎的犬。对10个身体部位进行了生物物理变量评估：腰部区域、右腋窝、右腹股沟区域、腹侧腹部区域、右外侧胸部区域、耳廓内表面、右前肢指间区域、脸颊、鼻梁以及前臂外侧部位。在以下区域发现SH与CADESI L之间存在正相关：腹股沟区域（r = 0.73）和指间区域（r = 0.82），以及数字区域的总CADESI与SH之间（r = 0.52）。此外，在腰部区域（r = 0.57）、右外侧胸部区域（r = 0.40）和前臂外侧（r = 0.35），皮肤pH值与CADESI L之间也报告了正相关。在指间区域发现红斑强度与总CADESI - 03（r = 0.60）以及CADESI L（r = 0.7）之间存在正相关。所获得的结果表明，可能可以使用皮肤水合作用、pH值和红斑强度来评估皮肤病变的严重程度，但仅在不到13.3%的可能相关性中发现了正相关，并且这些测量方法在犬类中的应用有限。
