Understanding of MYB Transcription Factors Involved in Glucosinolate Biosynthesis in Brassicaceae.

Glucosinolates (GSLs) are widely known secondary metabolites that have anticarcinogenic and antioxidative activities in humans and defense roles in plants of the Brassicaceae family. Some R2R3-type MYB (myeloblastosis) transcription factors (TFs) control GSL biosynthesis in . However, studies on the MYB TFs involved in GSL biosynthesis in species are limited because of the complexity of the genome, which includes an increased number of paralog genes as a result of genome duplication. The recent completion of the genome sequencing of the species permits the identification of MYB TFs involved in GSL biosynthesis by comparative genome analysis with . In this review, we describe various findings on the regulation of GSL biosynthesis in Brassicaceae. Furthermore, we identify 63 orthologous copies corresponding to five MYB TFs from , except MYB76 in species. Fifty-five MYB TFs from the species possess a conserved amino acid sequence in their R2R3 MYB DNA-binding domain, and share close evolutionary relationships. Our analysis will provide useful information on the 55 MYB TFs involved in the regulation of GSL biosynthesis in species, which have a polyploid genome.