多发伤所致全身炎症反应综合征和脓毒症中的生物标志物——一篇叙述性综述
Biomarkers in polytrauma induced systemic inflammatory response syndrome and sepsis - a narrative review.
作者信息
Trancă Sebastian Daniel, Petrişor Cristina Laura, Hagău Natalia
机构信息
Department of Anaesthesiology and Intensive Care, University of Medicine and Pharmacy "Iuliu Haţieganu" Cluj-Napoca, Romania.
出版信息
Rom J Anaesth Intensive Care. 2014 Oct;21(2):118-122.
Abstract
Polytrauma still represents one of the leading causes of death in the first four decades of life. Septic complications represent the predominant causes of late death in polytrauma patients. Early diagnosis and treatment of infection is associated with an improved clinical outcome and reduced mortality. Several biomarkers have been evaluated for making early diagnosis of sepsis. Current evidence does not support the use of a single biomarker in diagnosing septic complications. Procalcitonin trend was found to be useful in early identification of post-traumatic sepsis.
摘要
多发伤仍然是40岁前主要的死亡原因之一。脓毒症并发症是多发伤患者晚期死亡的主要原因。感染的早期诊断和治疗与改善临床结局及降低死亡率相关。已经评估了几种生物标志物用于脓毒症的早期诊断。目前的证据不支持使用单一生物标志物来诊断脓毒症并发症。发现降钙素原趋势在早期识别创伤后脓毒症方面有用。
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