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来自没食子树瘿瘤的两种具有一氧化氮和超氧化物抑制能力的新化合物。

Two New Compounds from the Galls of Quercus infectoria. with Nitric Oxide and Superoxide Inhibiting Ability.

作者信息

Hamid Hinna, Kaur Gurpreet, Abdullah S Tarique, Ali Mohammed, Athar Mohammad, Alam M Sarwar

机构信息

a Department of Chemistry, Faculty of Science, Jamia Hamdard, New Delhi, India.

b Department of Medical Elementology and Toxicology, Faculty of Science, Jaia Hamdard, New Delhi, India.

出版信息

Pharm Biol. 2005;43(4):317-323. doi: 10.1080/13880200590951711.

DOI:10.1080/13880200590951711
PMID:28925837
Abstract

Two compounds isolated from the ethanol extract of the galls of Quercus infectoria. Olivier exhibited nitric oxide (NO) and superoxide [Formula: see text] inhibiting activity. Their structures were established as ellagic acid-4-O.-[β.-D-glucopyranosyl]-10-O.-[β.-D-glucopyranosyl]-(4 → 1)-β.-D-rhamnopyranoside (1) and 2-methyl-3-hydroxymethylene-4,5,6,7,8-pentahydroxynaphthalene (2) on the basis of spectroscopic and chemical evidence.

摘要

从没食子(Quercus infectoria. Olivier)虫瘿乙醇提取物中分离得到的两种化合物表现出一氧化氮(NO)和超氧化物[化学式:见原文]抑制活性。基于光谱和化学证据,确定它们的结构分别为鞣花酸-4-O-[β-D-吡喃葡萄糖基]-10-O-[β-D-吡喃葡萄糖基]-(4→1)-β-D-鼠李吡喃糖苷(1)和2-甲基-3-羟基亚甲基-4,5,6,7,8-五羟基萘(2)。

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