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靶向癌症干细胞的新进展与挑战

New Advances and Challenges of Targeting Cancer Stem Cells.

作者信息

Dashzeveg Nurmaa K, Taftaf Rokana, Ramos Erika K, Torre-Healy Luke, Chumakova Anastasia, Silver Daniel J, Alban Tyler J, Sinyuk Maksim, Thiagarajan Praveena S, Jarrar Awad M, Turaga Soumya M, Saygin Caner, Mulkearns-Hubert Erin, Hitomi Masahiro, Rich Jeremy N, Gerson Stanton L, Lathia Justin D, Liu Huiping

机构信息

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio.

出版信息

Cancer Res. 2017 Oct 1;77(19):5222-5227. doi: 10.1158/0008-5472.CAN-17-0054. Epub 2017 Sep 19.

Abstract

The second International Cancer Stem Cell Conference in Cleveland, Ohio, on September 20-23, 2016, convened 330 attendees from academic, industrial, and clinical organizations. It featured a debate on the concepts and challenges of the cancer stem cells (CSC) as well as CSC-centered scientific sessions on clinical trials, genetics and epigenetics, tumor microenvironment, immune suppression, metastasis, therapeutic resistance, and emerging novel concepts. The conference hosted 35 renowned speakers, 100 posters, 20 short talks, and a preconference workshop. The reported advances of CSC research and therapies fostered new collaborations across national and international borders, and inspired the next generation's young scientists. .

摘要

2016年9月20日至23日,第二届国际癌症干细胞大会在俄亥俄州克利夫兰召开,来自学术、产业和临床机构的330名与会者齐聚一堂。会议围绕癌症干细胞(CSC)的概念与挑战展开了一场辩论,并举办了以CSC为中心的科学会议,内容涵盖临床试验、遗传学与表观遗传学、肿瘤微环境、免疫抑制、转移、治疗抗性以及新兴的新概念。此次会议邀请了35位知名演讲者,展示了100份海报、20个简短演讲,并举办了会前研讨会。会上所报道的CSC研究和治疗进展促成了跨国界的新合作,也激励了下一代年轻科学家。

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