Ando Akemi, Hagiya Hideharu, Nada Takahiro, Kimura Kosuke, Waseda Koichi, Rai Kammei, Hanayama Yoshihisa, Otsuka Fumio
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Japan.
Intern Med. 2017 Nov 15;56(22):3109-3112. doi: 10.2169/internalmedicine.9055-17. Epub 2017 Sep 25.
We herein report the first documented case of acute hypersensitivity pneumonitis in which Candida guilliermondii was the possible causative organism. A young Japanese woman presented to our hospital with relapsing respiratory symptoms accompanied by high fever. A detailed interview revealed that the onset of the symptoms occurred shortly after using a humidifier in her home. Her symptoms showed spontaneous improvement soon after admission, and an examination of her bronchoalveolar lavage fluid revealed the specific infiltration of inflammatory cells, which predominantly consisted of lymphocytes. Precipitin testing showed a positive reaction to C. guilliermondii, which was isolated from the home humidifier. Repeated history taking is essential for diagnosing occult respiratory disorders.
我们在此报告首例有记录的急性过敏性肺炎病例，其中季也蒙念珠菌可能是致病微生物。一名年轻日本女性因反复出现呼吸道症状并伴有高热前来我院就诊。详细询问病史发现，症状在她在家中使用加湿器后不久出现。入院后不久她的症状自行改善，对其支气管肺泡灌洗液的检查显示有炎症细胞的特异性浸润，主要由淋巴细胞组成。沉淀素试验显示对从家用加湿器中分离出的季也蒙念珠菌呈阳性反应。反复询问病史对于诊断隐匿性呼吸系统疾病至关重要。
