Wang Jingjing, Meng Xianwen, Dobrovolskaya Oxana B, Orlov Yuriy L, Chen Ming
Department of Bioinformatics, State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310058, China; James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, China.
Department of Bioinformatics, State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Genomics Proteomics Bioinformatics. 2017 Oct;15(5):301-312. doi: 10.1016/j.gpb.2017.01.007. Epub 2017 Oct 7.
Eukaryotic genomes encode thousands of non-coding RNAs (ncRNAs), which play crucial roles in transcriptional and post-transcriptional regulation of gene expression. Accumulating evidence indicates that ncRNAs, especially microRNAs (miRNAs) and long ncRNAs (lncRNAs), have emerged as key regulatory molecules in plant stress responses. In this review, we have summarized the current progress on the understanding of plant miRNA and lncRNA identification, characteristics, bioinformatics tools, and resources, and provided examples of mechanisms of miRNA- and lncRNA-mediated plant stress tolerance.
真核生物基因组编码数千种非编码RNA（ncRNA），它们在基因表达的转录和转录后调控中发挥着关键作用。越来越多的证据表明，ncRNA，尤其是微小RNA（miRNA）和长链非编码RNA（lncRNA），已成为植物应激反应中的关键调控分子。在这篇综述中，我们总结了目前在植物miRNA和lncRNA鉴定、特征、生物信息学工具及资源方面的理解进展，并提供了miRNA和lncRNA介导植物胁迫耐受性机制的实例。
