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PncStress:一个人工整理的实验验证的植物应激响应非编码 RNA 数据库。

PncStress: a manually curated database of experimentally validated stress-responsive non-coding RNAs in plants.

机构信息

Department of Bioinformatics, State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.

College of Life Sciences and Food Engineering, Inner Mongolia University for the Nationalities, Tongliao 028043, China.

出版信息

Database (Oxford). 2020 Jan 1;2020. doi: 10.1093/database/baaa001.

Abstract

Non-coding RNAs (ncRNAs) are recognized as key regulatory molecules in many biological processes. Accumulating evidence indicates that ncRNA-related mechanisms play important roles in plant stress responses. Although abundant plant stress-responsive ncRNAs have been identified, these experimentally validated results have not been gathered into a single public domain archive. Therefore, we established PncStress by curating experimentally validated stress-responsive ncRNAs in plants, including microRNAs, long non-coding RNAs and circular RNAs. The current version of PncStress contains 4227 entries from 114 plants covering 48 biotic and 91 abiotic stresses. For each entry, PncStress has biological information and network visualization. Serving as a manually curated database, PncStress will become a valuable resource in support of plant stress response research.

摘要

非编码 RNA(ncRNA)被认为是许多生物过程中的关键调节分子。越来越多的证据表明,ncRNA 相关机制在植物应激反应中发挥着重要作用。尽管已经鉴定出大量植物应激响应 ncRNA,但这些经过实验验证的结果尚未汇集到一个公共领域档案中。因此,我们通过整理植物中经过实验验证的应激响应 ncRNA,包括 microRNA、长非编码 RNA 和环状 RNA,建立了 PncStress。目前的 PncStress 版本包含 4227 个条目,来自 114 种植物,涵盖 48 种生物胁迫和 91 种非生物胁迫。对于每个条目,PncStress 都有生物学信息和网络可视化。作为一个人工整理的数据库,PncStress 将成为支持植物应激反应研究的宝贵资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfc5/7078067/6846524f87b7/baaa001f1.jpg

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