Kim Jong Min, Lee Hoyoung, Shin Jae Pil, Ahn Jeeyun, Yoo Je Moon, Song Su Jeong, Kim Sang Jin, Kang Se Woong
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Department of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea.
Korean J Ophthalmol. 2017 Dec;31(6):514-523. doi: 10.3341/kjo.2016.0098. Epub 2017 Aug 26.
To investigate the prevalence and risk factors for an epiretinal membrane (ERM) in Korean population.
Using the database of the Korea National Health and Nutrition Examination Survey from 2008 through 2012, 14,772 participants 40 years of age or older with gradable fundus photographs were included. The presence of ERM was determined by using fundus photographs. The prevalence of ERM was estimated and possible risk factors including systemic factors, nutritional status, and blood tests were analyzed via multiple logistic regression analyses.
The prevalence of ERM was 2.9% (95% confidence interval [CI], 2.6% to 3.3%). On multiple logistic regression analysis, the prevalence of ERM was affected by age. The odds ratios (ORs) against the forties were 2.70, 5.48, and 5.69 in the fifties, sixties, and seventies, respectively. ERM was also significantly affected by cataract surgery (OR, 2.82; 95% CI, 2.08 to 3.81) and by the increase in intake of 100-mg calcium (OR, 1.05; 95% CI, 1.00 to 1.11). ERM had negative associations with red blood cell count (OR, 0.66; 95% CI, 0.45 to 0.95).
The estimated nation-wide prevalence of ERM in Korea is 2.9%. The presence of ERM in the general population is associated with age, cataract surgery, increased dietary calcium, and a low red blood cell count.
调查韩国人群视网膜前膜（ERM）的患病率及危险因素。
利用2008年至2012年韩国国家健康与营养检查调查数据库，纳入14772名40岁及以上有可分级眼底照片的参与者。通过眼底照片确定ERM的存在。估计ERM的患病率，并通过多元逻辑回归分析分析包括全身因素、营养状况和血液检查在内的可能危险因素。
ERM的患病率为2.9%（95%置信区间[CI]，2.6%至3.3%）。多元逻辑回归分析显示，ERM的患病率受年龄影响。与四十多岁人群相比，五十多岁、六十多岁和七十多岁人群的优势比（OR）分别为2.70、5.48和5.69。ERM还受到白内障手术（OR，2.82；95%CI，2.08至3.81）和100毫克钙摄入量增加（OR，1.05；95%CI，1.00至1.11）的显著影响。ERM与红细胞计数呈负相关（OR，0.66；95%CI，0.45至0.95）。
韩国全国范围内ERM的估计患病率为2.9%。普通人群中ERM的存在与年龄、白内障手术、饮食钙增加和红细胞计数低有关。
