Allister Price Candice, Stanhope Kimber L
J Calif Dent Assoc. 2016 Oct 13;44(10):619-26.
The association between dietary sugar and type 2 diabetes (T2D) is likely mediated by the unregulated hepatic metabolism of fructose, which promotes hepatic and whole-body insulin resistance. Experimental evidence from clinical studies that utilize sensitive methods to test the effects of added sugar on insulin sensitivity is required. Establishing a causal link between added sugar and insulin resistance will help to stimulate health policies that target the reduction of added sugar consumption and T2D prevention.
膳食糖与2型糖尿病（T2D）之间的关联可能是由果糖不受调控的肝脏代谢介导的，这种代谢会促进肝脏和全身的胰岛素抵抗。需要来自临床研究的实验证据，这些研究采用灵敏的方法来测试添加糖对胰岛素敏感性的影响。建立添加糖与胰岛素抵抗之间的因果联系将有助于推动旨在减少添加糖消费和预防T2D的健康政策。
