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后路与前路清创联合植骨及内固定治疗胸腰椎结核

A posterior versus anterior debridement in combination with bone graft and internal fixation for lumbar and thoracic tuberculosis.

作者信息

Huang Yu, Lin Jin, Chen Xuanwei, Lin Jianhua, Lin Yulan, Zhang Hongjie

机构信息

Department of Spinal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China.

Department of Basic Medical Science, Fujian Medical College, Fuzhou, Fujian, China.

出版信息

J Orthop Surg Res. 2017 Oct 16;12(1):150. doi: 10.1186/s13018-017-0650-8.

Abstract

BACKGROUND

Surgery treatment is usually required for spinal tuberculosis. The aim of this study was to compare the clinical efficacy and outcomes of anterior and posterior surgical approach in combination with debridement, bone grafting, and internal fixation.

METHODS

All patients with thoracic and lumbar tuberculosis who underwent either the anterior or posterior surgery in combination with debridement, bone grafting, and internal fixation from August 2009 to August 2016 were reviewed retrospectively.

RESULTS

A total of 186 patients were recruited in the analyses, 37 of whom received the anterior approach and 149 treated with the posterior approach. In the entire study population, there was no statistically significant difference between the groups in terms of kyphosis Cobb's angle, VAS pain score, neurological status, operation duration, perioperative blood loss, and hospitalization days (p > 0.05). Good clinical outcomes were achieved in both treatment groups. In lumbar vertebra-affected patients, the average preoperative kyphosis Cobb's angle was 8.7 ± 16.6° and - 5.6 ± 16.0° for the anterior and posterior groups, respectively, which were corrected to - 3.3 ± 13.2° and - 10.1 ± 13.8° after surgery. For thoracic vertebra-affected patients, the corrected kyphosis Cobb's angle was 8.1 ± 9.7° and 10.3 ± 6.5°, respectively. After surgery, 32.4% of patients in the anterior group and 48.3% of patients in the posterior group claimed no pain (p = 0.24), while 83.8 and 85.9% recovered to Frankel grade E, respectively (p = 0.85).

CONCLUSIONS

The posterior debridement joint bone graft and internal fixation is an alternative procedure to treat lumbar and thoracic tuberculosis compared to the traditional anterior approach with similar clinical efficacy in terms of pain control, Cobb's angle, and neurological function. The posterior approach is sufficient for lesion debridement.

摘要

背景

脊柱结核通常需要手术治疗。本研究的目的是比较前路和后路手术联合清创、植骨及内固定的临床疗效和结果。

方法

回顾性分析2009年8月至2016年8月期间接受前路或后路手术联合清创、植骨及内固定的所有胸腰椎结核患者。

结果

共有186例患者纳入分析,其中37例接受前路手术,149例接受后路手术。在整个研究人群中,两组在脊柱后凸Cobb角、视觉模拟评分法(VAS)疼痛评分、神经功能状态、手术时间、围手术期失血量和住院天数方面差异无统计学意义(p>0.05)。两个治疗组均取得了良好的临床效果。在腰椎受累患者中,前路和后路组术前平均脊柱后凸Cobb角分别为8.7±16.6°和-5.6±16.0°,术后分别矫正至-3.3±13.2°和-10.1±13.8°。对于胸椎受累患者,矫正后的脊柱后凸Cobb角分别为8.1±9.7°和10.3±6.5°。术后,前路组32.4%的患者和后路组48.3%的患者表示无疼痛(p=0.24),而分别有83.8%和85.9%的患者恢复至Frankel E级(p=0.85)。

结论

与传统前路手术相比,后路清创联合植骨及内固定是治疗胸腰椎结核的一种替代方法,并在疼痛控制、Cobb角和神经功能方面具有相似的临床疗效。后路手术足以进行病灶清创。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09d0/5644256/9ffdd2a88009/13018_2017_650_Fig1_HTML.jpg

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