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生理生物力学加载对腰椎间盘内压和环应力的影响:有限元分析。

The Effects of Physiological Biomechanical Loading on Intradiscal Pressure and Annulus Stress in Lumbar Spine: A Finite Element Analysis.

机构信息

Faculty of Mechanical Engineering, Universiti Teknikal Malaysia Melaka, Hang Tuah Jaya, 76100 Durian Tunggal, Melaka, Malaysia.

Center for Robotics and Industrial Automation (CeRIA), Universiti Teknikal Malaysia Melaka, Hang Tuah Jaya, 76100 Durian Tunggal, Melaka, Malaysia.

出版信息

J Healthc Eng. 2017;2017:9618940. doi: 10.1155/2017/9618940. Epub 2017 Aug 27.

DOI:10.1155/2017/9618940
PMID:29065672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5592017/
Abstract

The present study was conducted to examine the effects of body weight on intradiscal pressure (IDP) and annulus stress of intervertebral discs at lumbar spine. Three-dimensional finite element model of osseoligamentous lumbar spine was developed subjected to follower load of 500 N, 800 N, and 1200 N which represent the loads for individuals who are normal and overweight with the pure moments at 7.5 Nm in flexion and extension motions. It was observed that the maximum IDP was 1.26 MPa at L1-L2 vertebral segment. However, the highest increment of IDP was found at L4-L5 segment where the IDP was increased to 30% in flexion and it was more severe at extension motion reaching to 80%. Furthermore, the maximum annulus stress also occurred at the L1-L2 segment with 3.9 MPa in extension motion. However, the highest increment was also found at L4-L5 where the annulus stress increased to 17% in extension motion. Based on these results, the increase of physiological loading could be an important factor to the increment of intradiscal pressure and annulus fibrosis stress at all intervertebral discs at the lumbar spine which may lead to early intervertebral disc damage.

摘要

本研究旨在探讨体重对腰椎间盘内压(IDP)和椎间盘环应力的影响。建立了骨-韧带腰椎的三维有限元模型,在屈伸运动中分别施加 500N、800N 和 1200N 的跟从载荷(分别代表正常体重和超重个体的载荷)以及 7.5Nm 的纯力矩。结果观察到,L1-L2 节段的最大 IDP 为 1.26MPa。然而,IDP 增加幅度最大的是在 L4-L5 节段,在屈伸运动中增加了 30%,在伸展运动中更为严重,达到了 80%。此外,在伸展运动中,最大的环应力也发生在 L1-L2 节段,为 3.9MPa。然而,增加幅度最大的仍然是在 L4-L5 节段,环应力增加了 17%。基于这些结果,生理负荷的增加可能是导致腰椎所有椎间盘内压和环纤维应力增加的一个重要因素,这可能导致早期椎间盘损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/7e4d551da3ae/JHE2017-9618940.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/e0541ea75bd2/JHE2017-9618940.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/94ce080cddee/JHE2017-9618940.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/7e976e2306b6/JHE2017-9618940.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/8f4f5d967624/JHE2017-9618940.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/f5cf6c2a287b/JHE2017-9618940.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/54b8ee194680/JHE2017-9618940.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/7e4d551da3ae/JHE2017-9618940.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/e0541ea75bd2/JHE2017-9618940.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/94ce080cddee/JHE2017-9618940.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/7e976e2306b6/JHE2017-9618940.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/8f4f5d967624/JHE2017-9618940.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/f5cf6c2a287b/JHE2017-9618940.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/54b8ee194680/JHE2017-9618940.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db69/5592017/7e4d551da3ae/JHE2017-9618940.007.jpg

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