Shava Upender, Srivastava Anshu, Mathias Amrita, Yachha Surender Kumar, Poddar Ujjal
Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India.
Indian J Gastroenterol. 2017 Sep;36(5):405-410. doi: 10.1007/s12664-017-0794-9. Epub 2017 Oct 25.
Nutrient drink test (NDT) is a simple, non-invasive method to assess gastric function including accommodation. However, data on normal satiety drink volume (SDV) in children is scanty with no information about postprandial symptoms (PPS). Our aims were to establish normal values of NDT in healthy children and evaluate its correlation with age, gender, and anthropometry.
Six- to 18-year-old healthy children underwent the NDT. The nutrient drink (0.94 kcal/mL) was given at a constant rate of 15 mL/min in 6-12-year-old subjects and at 30 mL/min in 13-18-year-old subjects till satiety score of 5 was reached. Postprandial symptoms (30 min) of fullness, nausea, bloating, and pain were scored using a visual analogue scale (0-100 mm) individually and as aggregate score.
Sixty-seven children (40 boys, age 12 [6-18 years]) were enrolled. Median SDV was 360 [180-960 mL], higher in 13-18-year-olds in comparison to 6-12-year-old children (360 [240-1002] vs. 300 [148-960] mL; p=0.005). SDV showed significant correlation with age, weight, and height. SDV was higher in boys than girls (450 [240-1074] vs. 330 [240-480] mL; p=0.02) in the older children (13-18 y), but it was similar in the younger children. Mild fullness (40 [0-80]) was the only PPS seen in 85% children and none had pain. PPS were not different between boys and girls or younger and older children.
The study provides normative data of SDV and PPS by NDT in 6-18-year-old children. SDV correlated with age and was higher in adolescent boys than girls.
营养饮料测试（NDT）是一种评估包括胃容纳功能在内的胃功能的简单、非侵入性方法。然而，关于儿童正常饱腹感饮料量（SDV）的数据很少，且没有关于餐后症状（PPS）的信息。我们的目的是确定健康儿童NDT的正常值，并评估其与年龄、性别和人体测量学的相关性。
6至18岁的健康儿童接受NDT。在6至12岁的受试者中，以15毫升/分钟的恒定速率给予营养饮料（0.94千卡/毫升），在13至18岁的受试者中以30毫升/分钟的速率给予，直至饱腹感评分为5。使用视觉模拟量表（0 - 100毫米）分别对饱腹感、恶心、腹胀和疼痛的餐后症状（30分钟）进行评分，并计算总评分。
纳入了67名儿童（40名男孩，年龄12岁[6 - 18岁]）。SDV中位数为360[180 - 960毫升]，13至18岁儿童的SDV高于6至12岁儿童（360[240 - 1002]对300[148 - 960]毫升；p = 0.005）。SDV与年龄、体重和身高显著相关。在年龄较大的儿童（13至18岁）中，男孩的SDV高于女孩（450[240 - 1074]对330[240 - 480]毫升；p = 0.02），但在年龄较小的儿童中相似。85%的儿童仅出现轻度饱腹感（40[0 - 80]），且无疼痛症状。男孩和女孩之间以及年龄较小和较大的儿童之间的PPS没有差异。
该研究提供了6至18岁儿童通过NDT获得的SDV和PPS的规范数据。SDV与年龄相关，青春期男孩的SDV高于女孩。
