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来自塞浦路斯首例西尼罗河病毒（WNV）神经侵袭性感染人类病例的西尼罗河病毒全基因组序列

Complete Genome Sequence of West Nile Virus (WNV) from the First Human Case of Neuroinvasive WNV Infection in Cyprus.

作者信息

Richter Jan, Tryfonos Christina, Tourvas Aristomenis, Floridou Dora, Paphitou Niki I, Christodoulou Christina

机构信息

Department of Molecular Virology, Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus

Department of Molecular Virology, Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

出版信息

Genome Announc. 2017 Oct 26;5(43):e01110-17. doi: 10.1128/genomeA.01110-17.

DOI:10.1128/genomeA.01110-17
PMID:29074649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5658487/
Abstract

We report here the complete genome sequence of a West Nile virus (WNV) strain from the first laboratory-confirmed human case of neuroinvasive WNV infection in Cyprus. Phylogenetic analysis showed that this WNV strain grouped clearly into genetic lineage 1, clade 1a, cluster 2.

摘要

我们在此报告来自塞浦路斯首例实验室确诊的西尼罗河病毒（WNV）神经侵袭性感染人类病例的一株WNV的全基因组序列。系统发育分析表明，该WNV毒株明显归为基因1型、1a分支、2簇。

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本文引用的文献

1
The first human case of neuroinvasive West Nile virus infection identified in Cyprus.塞浦路斯发现首例西尼罗河病毒神经侵袭性感染的人类病例。
J Infect Public Health. 2017 Nov-Dec;10(6):891-893. doi: 10.1016/j.jiph.2017.02.003. Epub 2017 Feb 21.
2
First isolation of West Nile virus from a dromedary camel.首次从单峰骆驼中分离出西尼罗河病毒。
Emerg Microbes Infect. 2016 Jun 8;5(6):e53. doi: 10.1038/emi.2016.53.
3
MEGA6: Molecular Evolutionary Genetics Analysis version 6.0.MEGA6：分子进化遗传学分析版本 6.0。
Mol Biol Evol. 2013 Dec;30(12):2725-9. doi: 10.1093/molbev/mst197. Epub 2013 Oct 16.
4
Comparison of phi29-based whole genome amplification and whole transcriptome amplification in dengue virus.基于 phi29 的全基因组扩增与全转录组扩增在登革病毒中的比较。
J Virol Methods. 2014 Jan;195:141-7. doi: 10.1016/j.jviromet.2013.10.005. Epub 2013 Oct 12.
5
Phylogeography of West Nile virus: from the cradle of evolution in Africa to Eurasia, Australia, and the Americas.西尼罗河病毒的系统地理学研究：从非洲的起源地到欧亚大陆、澳大利亚和美洲。
J Virol. 2011 Mar;85(6):2964-74. doi: 10.1128/JVI.01963-10. Epub 2010 Dec 15.
6
West Nile virus.西尼罗河病毒
Clin Lab Med. 2010 Mar;30(1):47-65. doi: 10.1016/j.cll.2009.10.006.
7
The mosquito fauna of the Republic of Cyprus: a revised list.塞浦路斯共和国的蚊虫种类：一份修订清单。
J Am Mosq Control Assoc. 2009 Jun;25(2):199-202. doi: 10.2987/08-5793.1.
8
West Nile virus.西尼罗河病毒
Lancet Neurol. 2007 Feb;6(2):171-81. doi: 10.1016/S1474-4422(07)70030-3.
9
N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity.西尼罗河病毒包膜蛋白的N-连接糖基化影响病毒粒子组装和感染性。
J Virol. 2005 Nov;79(21):13262-74. doi: 10.1128/JVI.79.21.13262-13274.2005.
10
Complete genome sequences and phylogenetic analysis of West Nile virus strains isolated from the United States, Europe, and the Middle East.从美国、欧洲和中东分离出的西尼罗河病毒株的全基因组序列及系统发育分析。
Virology. 2002 Jun 20;298(1):96-105. doi: 10.1006/viro.2002.1449.