Özkan Mine, Yıldırım Nazmiye, Dişçi Rian, İlgün Ahmet Serkan, Sarsenov Dauren, Alço Gül, Aktepe Fatma, Kalyoncu Nesiba, İzci Filiz, Selamoğlu Derya, Ordu Çetin, Pilancı Kezban Nur, Erdoğan Zeynep İyigün, Eralp Yeşim, Özmen Vahit
Department of Consultation Liaison Psychiatry, İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey.
Department of Public Health, İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey.
Eur J Breast Health. 2017 Oct 1;13(4):206-212. doi: 10.5152/ejbh.2017.3519. eCollection 2017 Oct.
The aim of this study was to determine the roles of biopsychosocial risk factors in the development of breast cancer.
This hospital-based case-control study included 491 women with breast cancer (study group) and 512 women who did not have cancer or other serious diseases (control group). Biological, psychological, and social risk factors were compared between the two groups. Data were collected using the semi-structured interview, the Stress Assessment Form, and the Coping Strategy Indicator to assess these factors.
When the significantly different biopsychosocial variables between the study and the control groups were evaluated together, independent breast cancer risk factors were found as follows: a stressor experienced in the last 5 years, age 40 years and older, inadequate social support perception, use of avoidance coping strategy, being a housewife, having a family history of cancer, and having a body mass index ≥25.
This study showed a relationship between breast cancer risk and manageable variables (obesity, stressor and coping strategy, social support, and employment status), age and family history of cancer, which are biopsychosocial factors. Biopsychosocial aspects are becoming a greater part of many different healthcare systems.
本研究旨在确定生物心理社会风险因素在乳腺癌发生发展中的作用。
本基于医院的病例对照研究纳入了491例乳腺癌女性(研究组)和512例无癌症或其他严重疾病的女性(对照组)。比较了两组之间的生物、心理和社会风险因素。使用半结构化访谈、压力评估表和应对策略指标收集数据以评估这些因素。
当对研究组和对照组之间显著不同的生物心理社会变量进行综合评估时,发现独立的乳腺癌风险因素如下:过去5年经历过应激源、年龄40岁及以上、社会支持感知不足、使用回避应对策略、家庭主妇身份、有癌症家族史以及体重指数≥25。
本研究表明乳腺癌风险与可控制变量(肥胖、应激源和应对策略、社会支持及就业状况)、年龄以及癌症家族史之间存在关联,这些均为生物心理社会因素。生物心理社会层面正成为许多不同医疗保健系统中越来越重要的一部分。