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本文引用的文献

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Subarachnoid hemorrhage - Induced block of cerebrospinal fluid flow: Role of brain coagulation factor III (tissue factor).蛛网膜下腔出血 - 脑脊液流动受阻:脑凝血因子 III(组织因子)的作用。
J Cereb Blood Flow Metab. 2018 May;38(5):793-808. doi: 10.1177/0271678X17701157. Epub 2017 Mar 28.
2
Chronic Trigemino-Cardiac Reflex: An Underestimated Truth.慢性三叉神经-心脏反射:一个被低估的真相。
Front Neurol. 2017 Jan 30;8:22. doi: 10.3389/fneur.2017.00022. eCollection 2017.
3
The negative chronotropic effect during lumbar spine surgery: A systemic review and aggregation of an emerging model of spinal cardiac reflex.腰椎手术期间的负性变时效应:对一种新兴的脊髓心脏反射模型的系统评价与汇总分析
Medicine (Baltimore). 2017 Jan;96(1):e5436. doi: 10.1097/MD.0000000000005436.
4
Sudden Infant Death Syndrome - Role of Trigeminocardiac Reflex: A Review.婴儿猝死综合征——三叉神经心脏反射的作用:综述
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5
The Role of Acute Trigemino-Cardiac Reflex in Unusual, Non-Surgical Cases: A Review.急性三叉神经-心脏反射在罕见非手术病例中的作用:综述
Front Neurol. 2016 Oct 26;7:186. doi: 10.3389/fneur.2016.00186. eCollection 2016.
6
Diving Response in Rats: Role of the Subthalamic Vasodilator Area.大鼠的潜水反应:丘脑底血管舒张区的作用。
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7
Hypoxia and hypercapnia inhibit hypothalamic orexin neurons in rats.缺氧和高碳酸血症会抑制大鼠下丘脑的食欲素神经元。
J Neurophysiol. 2016 Nov 1;116(5):2250-2259. doi: 10.1152/jn.00196.2016. Epub 2016 Aug 24.
8
The Trigemino-cardiac Reflex: Is Treatment With Atropine Still Justified?三叉神经-心脏反射:阿托品治疗是否仍合理?
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9
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Medicine (Baltimore). 2016 May;95(22):e3733. doi: 10.1097/MD.0000000000003733.
10
How to apply case reports in clinical practice using surrogate models via example of the trigeminocardiac reflex.如何通过三叉神经心脏反射的实例,运用替代模型将病例报告应用于临床实践。
J Med Case Rep. 2016 Apr 6;10:84. doi: 10.1186/s13256-016-0849-z.

三叉神经心脏反射的定义与诊断:一种用于更新的扎根理论方法

Definition and Diagnosis of the Trigeminocardiac Reflex: A Grounded Theory Approach for an Update.

作者信息

Meuwly Cyrill, Chowdhury Tumul, Sandu Nora, Golanov Eugene, Erne Paul, Rosemann Thomas, Schaller Bernhard

机构信息

University Hospital Basel, Basel, Switzerland.

Department of Anaesthesiology and Perioperative Medicine, University of Manitoba, Winnipeg, MB, Canada.

出版信息

Front Neurol. 2017 Oct 9;8:533. doi: 10.3389/fneur.2017.00533. eCollection 2017.

DOI:10.3389/fneur.2017.00533
PMID:29085328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649131/
Abstract

BACKGROUND

The trigeminocardiac reflex (TCR) is defined as sudden onset of parasympathetic dysrhythmias including hemodynamic irregularities, apnea, and gastric hypermotility during stimulation of sensory branches of the trigeminal nerve. Since the first description of the TCR in 1999, there is an ongoing discussion about a more emergent clinical definition. In this work, the author worked out an approach to such an improved definition.

METHODS

In this study, a grounded theory approach was used. Literature about TCR was systematically identified through PubMed (MEDLINE), EMBASE (Ovid SP), and ISI Web of Sciences databases from 1/2005 until 8/2015. TCR was defined as a drop of heart rate (HR) below 60 bpm or 20% to the baseline. A grounded theory approach was used to analyze and interpret the data through a synthesis by the researcher's perspectives, values, and positions.

RESULTS

Out of the included studies, the authors formed available data to an update of the understanding of changes in hemodynamic parameters (HR and blood pressure) in a TCR. According to this update, an HR deceleration should be a constant observation to identify a TCR episode while a drop in blood pressure should probably not being fixed to a certain percentage of decrease.

CONCLUSION

The here presented working definition improves our understanding of the TCR. It leads the way to a new understanding of the TCR for a proper clinical definition.

摘要

背景

三叉神经心脏反射(TCR)被定义为在刺激三叉神经感觉分支期间突然出现的副交感神经节律失常,包括血流动力学异常、呼吸暂停和胃动力亢进。自1999年首次描述TCR以来,关于更紧急的临床定义的讨论一直在进行。在这项工作中,作者制定了一种改进定义的方法。

方法

在本研究中,采用了扎根理论方法。通过PubMed(MEDLINE)、EMBASE(Ovid SP)和ISI Web of Sciences数据库,从2005年1月至2015年8月系统地识别了有关TCR的文献。TCR被定义为心率(HR)降至60次/分以下或降至基线的20%。采用扎根理论方法,通过研究者的观点、价值观和立场进行综合分析和解释数据。

结果

在纳入的研究中,作者整理了现有数据,以更新对TCR中血流动力学参数(HR和血压)变化的理解。根据这一更新,HR减速应该是识别TCR发作的持续观察指标,而血压下降可能不应固定在一定的下降百分比上。

结论

本文提出的工作定义提高了我们对TCR的理解。它为正确的临床定义带来了对TCR的新理解。