Meuwly Cyrill, Chowdhury Tumul, Sandu Nora, Golanov Eugene, Erne Paul, Rosemann Thomas, Schaller Bernhard
University Hospital Basel, Basel, Switzerland.
Department of Anaesthesiology and Perioperative Medicine, University of Manitoba, Winnipeg, MB, Canada.
Front Neurol. 2017 Oct 9;8:533. doi: 10.3389/fneur.2017.00533. eCollection 2017.
The trigeminocardiac reflex (TCR) is defined as sudden onset of parasympathetic dysrhythmias including hemodynamic irregularities, apnea, and gastric hypermotility during stimulation of sensory branches of the trigeminal nerve. Since the first description of the TCR in 1999, there is an ongoing discussion about a more emergent clinical definition. In this work, the author worked out an approach to such an improved definition.
In this study, a grounded theory approach was used. Literature about TCR was systematically identified through PubMed (MEDLINE), EMBASE (Ovid SP), and ISI Web of Sciences databases from 1/2005 until 8/2015. TCR was defined as a drop of heart rate (HR) below 60 bpm or 20% to the baseline. A grounded theory approach was used to analyze and interpret the data through a synthesis by the researcher's perspectives, values, and positions.
Out of the included studies, the authors formed available data to an update of the understanding of changes in hemodynamic parameters (HR and blood pressure) in a TCR. According to this update, an HR deceleration should be a constant observation to identify a TCR episode while a drop in blood pressure should probably not being fixed to a certain percentage of decrease.
The here presented working definition improves our understanding of the TCR. It leads the way to a new understanding of the TCR for a proper clinical definition.
三叉神经心脏反射(TCR)被定义为在刺激三叉神经感觉分支期间突然出现的副交感神经节律失常,包括血流动力学异常、呼吸暂停和胃动力亢进。自1999年首次描述TCR以来,关于更紧急的临床定义的讨论一直在进行。在这项工作中,作者制定了一种改进定义的方法。
在本研究中,采用了扎根理论方法。通过PubMed(MEDLINE)、EMBASE(Ovid SP)和ISI Web of Sciences数据库,从2005年1月至2015年8月系统地识别了有关TCR的文献。TCR被定义为心率(HR)降至60次/分以下或降至基线的20%。采用扎根理论方法,通过研究者的观点、价值观和立场进行综合分析和解释数据。
在纳入的研究中,作者整理了现有数据,以更新对TCR中血流动力学参数(HR和血压)变化的理解。根据这一更新,HR减速应该是识别TCR发作的持续观察指标,而血压下降可能不应固定在一定的下降百分比上。
本文提出的工作定义提高了我们对TCR的理解。它为正确的临床定义带来了对TCR的新理解。