以氟代烷基碘化物作为氟烷基化试剂，光诱导、铜催化的烯烃三组分氰基氟烷基化反应。
Photoinduced, copper-catalyzed three components cyanofluoroalkylation of alkenes with fluoroalkyl iodides as fluoroalkylation reagents.
作者信息
Guo Quanping, Wang Mengran, Wang Yanfang, Xu Zhaoqing, Wang Rui
机构信息
Key Laboratory of Preclinical Study for New Drugs of Gansu Province, The Institute of Pharmacology, School of Basic Medical Science, Lanzhou University, 199 West Donggang Road, Lanzhou 730000, China.
出版信息
Chem Commun (Camb). 2017 Nov 14;53(91):12317-12320. doi: 10.1039/c7cc07128k.
In the past few years, Ru and Ir catalyzed photoredox radical coupling reactions have been widely applied in organic synthesis. In contrast, the applications of Cu catalysts in photoredox organic transformations were limited. We here report the first example of photoinduced, Cu-catalyzed three component cyanofluoroalkylation of alkenes by directly using fluoroalkyl iodides as fluoroalkylation reagents.
在过去几年中，钌和铱催化的光氧化还原自由基偶联反应已在有机合成中得到广泛应用。相比之下，铜催化剂在光氧化还原有机转化中的应用有限。我们在此报告首例通过直接使用碘氟代烷作为氟烷基化试剂，光诱导、铜催化的烯烃三组分氰基氟烷基化反应。
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