Health Policy Center, Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, Illinois, USA.
School of Public Health, Georgia State University, Atlanta, Georgia, USA.
Tob Control. 2018 Oct;27(e2):e152-e159. doi: 10.1136/tobaccocontrol-2017-053754. Epub 2017 Nov 2.
To examine the impact of flavour, device type and health warning messages on youth preference for electronic nicotine delivery systems (ENDS), and to provide evidence and data to inform the Food and Drug Administration's potential regulatory actions on ENDS.
An online discrete choice experiment was conducted in September 2015. Each participant was given nine choice sets and asked to choose one out of two alternative ENDS products, with varying characteristics in three attributes (flavour, device type and warning message). The impact of the attributes on the probability of choosing ENDS was analysed using conditional and nested logit regressions, controlling for individual sociodemographic characteristics and current smoking status.
A general population sample of 515 participants (50 ever-users and 465 never-users of ENDS) aged 14-17 years were recruited to complete the experiment using an online panel.
Fruit/sweets/beverage flavours significantly increase the probability of choosing ENDS among youth (p<0.01 for never-users and <0.1 for ever-users) and flavour has the most pronounced impact among three attributes. Among never-users, menthol flavour also increases (p<0.05) the probability of choosing ENDS compared with tobacco flavour. Vaping devices that are modifiable, compared with cigarette-like e-cigarettes, increase (p<0.05) the probability of choosing ENDS among adolescent never-users. Warning messages reduce (p<0.01) the probability of choosing ENDS among never-users.
Restricting fruit/sweets/beverage flavours in ENDS, regulating modifiable vaping devices and adopting strong health warning messages may reduce the uptake of ENDS among youth.
研究口味、装置类型和健康警示信息对青少年选择电子尼古丁传送系统（ENDS）的影响，并为食品和药物管理局对 ENDS 进行潜在监管行动提供证据和数据。
2015 年 9 月进行了一项在线离散选择实验。每个参与者都会获得九个选择集，并被要求从两个可供选择的 ENDS 产品中选择一个，这些产品在三个属性（口味、装置类型和警示信息）上具有不同的特点。使用条件和嵌套对数回归分析，控制个体社会人口特征和当前吸烟状况，分析这些属性对选择 ENDS 的概率的影响。
使用在线小组招募了 515 名年龄在 14-17 岁的一般人群参与者（50 名 ENDS 既往使用者和 465 名从未使用者）完成实验。
水果/糖果/饮料口味显著增加了青少年选择 ENDS 的概率（从未使用者为 <0.01，既往使用者为 <0.1），并且在三个属性中口味的影响最为显著。在从未使用者中，薄荷醇口味也比烟草口味更能增加选择 ENDS 的概率（p<0.05）。与类似香烟的电子烟相比，可改装的蒸气装置增加了青少年从未使用者选择 ENDS 的概率（p<0.05）。警示信息降低了从未使用者选择 ENDS 的概率（p<0.01）。
限制 ENDS 中的水果/糖果/饮料口味、规范可改装的蒸气装置和采用强有力的健康警示信息，可能会降低青少年对 ENDS 的使用率。
