Iacopetti Ilaria, Perazzi Anna, Badon Tamara, Bedin Silvia, Contiero Barbara, Ricci Rebecca
Department of Animal Medicine, Production and Health, University of Padua, Legnaro (Padua), Italy.
BMC Vet Res. 2017 Nov 10;13(1):330. doi: 10.1186/s12917-017-1256-4.
Saliva in dogs, as in humans, is a complex fluid secreted by different salivary glands in the oral cavity to protect the oral mucosa and teeth. The use of saliva as a substitute for blood in diagnosing and prognosticating disease in humans is widely accepted. Salivary biochemistry has also been used as a marker for periodontal disease in humans. No studies have as yet investigated the relation between salivary biochemistry and periodontal disease in dogs, however; neither has the salivary composition of healthy dogs with no oral disease been assessed. The purpose of this study was to obtain an overview on pH distribution and a set of salivary biochemical analytes (calcium, phosphorus, lactate dehydrogenase, lysozyme and amylase) commonly related to oral health in humans in a subset population of healthy young dogs with no periodontal disease or previous oral disease. Data were analyzed to gather salivary reference ranges for pH and each parameter and to assess a possible correlation between salivary and serum analytes.
Twenty-nine adult client-owned dogs were recruited for the study. Lactate dehydrogenase and lysozyme showed higher concentrations in saliva than in serum, whereas amylase showed the contrary. Salivary biochemistry values did not differ between males and females or between non-neutered and neutered individuals. No significant correlations between salivary and serum calcium, phosphorus, lactate dehydrogenase, amylase and lysozyme were identified in this study. Data allowed intervals for the salivary pH and other analytes investigated to be obtained from healthy dogs with healthy oral conditions.
These preliminary data can contribute to enlarge our understanding of the functional role of saliva and its relation to oral health in dogs.
与人类一样，犬类的唾液是口腔中不同唾液腺分泌的一种复杂液体，用于保护口腔黏膜和牙齿。在人类疾病诊断和预后评估中，使用唾液替代血液已被广泛接受。唾液生物化学也已被用作人类牙周疾病的标志物。然而，目前尚无研究调查犬类唾液生物化学与牙周疾病之间的关系；也未评估无口腔疾病的健康犬类的唾液成分。本研究的目的是在一组无牙周疾病或既往口腔疾病的健康幼犬亚群中，概述pH分布以及一组通常与人类口腔健康相关的唾液生化分析物（钙、磷、乳酸脱氢酶、溶菌酶和淀粉酶）。对数据进行分析，以收集pH值和各参数的唾液参考范围，并评估唾液和血清分析物之间可能存在的相关性。
本研究招募了29只成年客户拥有的犬只。乳酸脱氢酶和溶菌酶在唾液中的浓度高于血清，而淀粉酶则相反。唾液生化值在雄性和雌性之间或未绝育和绝育个体之间没有差异。本研究未发现唾液与血清钙、磷、乳酸脱氢酶、淀粉酶和溶菌酶之间存在显著相关性。数据使得能够从口腔状况健康的健康犬只中获得唾液pH值和其他所研究分析物的区间。
这些初步数据有助于扩大我们对犬类唾液功能作用及其与口腔健康关系的理解。
