利用产油酵母粘红酵母IFO0880 从 D-木糖生产 D-阿拉伯糖醇。
Production of D-arabitol from D-xylose by the oleaginous yeast Rhodosporidium toruloides IFO0880.
机构信息
Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave., Urbana, IL, 61801, USA.
出版信息
Appl Microbiol Biotechnol. 2018 Jan;102(1):143-151. doi: 10.1007/s00253-017-8581-1. Epub 2017 Nov 11.
The sugar alcohol D-arabitol is one of the Department of Energy's top twelve bio-based building block chemicals. In this study, we found that the oleaginous yeast Rhodosporidium toruloides IFO0880 produces D-arabitol during growth on xylose in nitrogen-rich medium. Efficient xylose utilization was a prerequisite for extracellular D-arabitol production. During growth in complex media, R. toruloides produced 22 ± 2, 32 ± 2, and 49 ± 2 g/L D-arabitol from 70, 105, and 150 g/L xylose, respectively. In addition, we found that R. toruloides could potentially be used for the co-production of lipids and D-arabitol from xylose. These results demonstrate that R. toruloides can be used to produce multiple value-added chemicals from xylose.
糖醇 D-阿拉伯糖醇是能源部十二种顶级生物基建筑用化学品之一。在这项研究中，我们发现产油酵母 Rhodosporidium toruloides IFO0880 在富氮培养基中利用木糖生长时会产生 D-阿拉伯糖醇。高效利用木糖是细胞外 D-阿拉伯糖醇生产的前提。在复杂培养基中生长时，R. toruloides 分别从 70、105 和 150 g/L 木糖中生产 22±2、32±2 和 49±2 g/L 的 D-阿拉伯糖醇。此外，我们发现 R. toruloides 可能可用于从木糖共生产脂质和 D-阿拉伯糖醇。这些结果表明，R. toruloides 可用于从木糖生产多种高附加值化学品。
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