仅从消化性溃疡患者和慢性胃炎患者中分离出的幽门螺杆菌菌株产生细胞毒素的情况。
Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only.
作者信息
Figura N, Guglielmetti P, Rossolini A, Barberi A, Cusi G, Musmanno R A, Russi M, Quaranta S
机构信息
Istituto di Malattie Infettive, Università di Siena, Italy.
出版信息
J Clin Microbiol. 1989 Jan;27(1):225-6. doi: 10.1128/jcm.27.1.225-226.1989.
Abstract
A total of 66.6% of Campylobacter pylori strains isolated from patients with peptic ulcers produced a cytotoxin active against mammalian cells in vitro, versus 30.1% of strains isolated from patients with chronic gastritis of various degrees of severity only. This difference was statistically significant and suggests that the toxic substance could be involved in the development of peptic ulcers.
摘要
从消化性溃疡患者中分离出的幽门螺杆菌菌株，共有66.6%在体外产生了对哺乳动物细胞具有活性的细胞毒素，而从不同严重程度的慢性胃炎患者中分离出的菌株只有30.1%产生该毒素。这种差异具有统计学意义，表明该有毒物质可能与消化性溃疡的发生有关。
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