Ragulator-溶酶体信号和运输的多效调节因子。
Ragulator-a multifaceted regulator of lysosomal signaling and trafficking.
机构信息
Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Copenhagen, Denmark.
Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Copenhagen, Denmark
出版信息
J Cell Biol. 2017 Dec 4;216(12):3895-3898. doi: 10.1083/jcb.201710039. Epub 2017 Nov 14.
The lysosomal Ragulator complex regulates cell metabolism and growth by coordinating the activities of metabolic signaling pathways with nutrient availability. In this issue, Filipek et al. (2017. https://doi.org/10.1083/jcb.201703061) and Pu et al. (2017. https://doi.org/10.1083/jcb.201703094) introduce a role for Ragulator in growth factor- and nutrient-regulated lysosomal trafficking.
溶酶体 Ragulator 复合物通过协调代谢信号通路的活性与营养可用性来调节细胞代谢和生长。在本期中，Filipek 等人（2017. https://doi.org/10.1083/jcb.201703061）和 Pu 等人（2017. https://doi.org/10.1083/jcb.201703094）介绍了 Ragulator 在生长因子和营养物质调节的溶酶体运输中的作用。
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