Chan A Y, Swaminathan R, Cockram C S
Department of Chemical Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin.
Clin Chem. 1989 Feb;35(2):315-7.
How effective is sodium fluoride as a preservative of blood glucose? We compared changes in glucose concentration in fluoride-treated blood specimens with those of heparin-treated specimens. The former declined rapidly during the first hour; thereafter the rate of decrease was slower, and after 4 h the glucose concentration in the blood samples remained stable for up to three days. In contrast, the glucose concentration in the heparin-containing samples declined continuously. During the first hour, however, the rates of decline in the two types of samples were similar. Evidently sodium fluoride takes effect slowly but effectively in preserving glucose in blood for at least three days. Its use, however, is unnecessary if the concentration of glucose is to be measured within the first hour after sampling.
氟化钠作为血糖防腐剂的效果如何？我们比较了经氟化物处理的血样与经肝素处理的血样中葡萄糖浓度的变化。前者在最初一小时内迅速下降；此后下降速度较慢，4小时后血样中的葡萄糖浓度在长达三天的时间内保持稳定。相比之下，含肝素的样本中葡萄糖浓度持续下降。然而，在最初一小时内，两种样本的下降速率相似。显然，氟化钠在保存血液中的葡萄糖方面起效缓慢但至少能有效保存三天。然而，如果要在采样后第一小时内测量葡萄糖浓度，则无需使用它。
