CSMBLM, Committee for the scientific professional development, Working group for uncertainty of measurement of the CSMBLM and CCMB, Croatia.
Department of Clinical Chemistry, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Biochem Med (Zagreb). 2017 Oct 15;27(3):030502. doi: 10.11613/BM.2017.030502.
The International vocabulary of metrology - Basic and general concepts and associated terms (VIM3, 2.26 measurement uncertainty, JCGM 200:2012) defines uncertainty of measurement as a non-negative parameter characterizing the dispersion of the quantity values being attributed to a measurand, based on the information obtained from performing the measurement. Clinical Laboratory Standards Institute (CLSI) has published a very detailed guideline with a description of sources contributing to measurement uncertainty as well as different approaches for the calculation (Expression of measurement uncertainty in laboratory medicine; Approved Guideline, CLSI C51-A 2012). Many other national and international recommendations and original scientific papers about measurement uncertainty estimation have been published. In Croatia, the estimation of measurement uncertainty is obligatory for accredited medical laboratories. However, since national recommendations are currently not available, each of these laboratories uses a different approach in measurement uncertainty estimation. The main purpose of this document is to describe the minimal requirements for measurement uncertainty estimation. In such way, it will contribute to the harmonization of measurement uncertainty estimation, evaluation and reporting across laboratories in Croatia. This recommendation is issued by the joint Working group for uncertainty of measurement of the Croatian Society for Medical Biochemistry and Laboratory Medicine and Croatian Chamber of Medical Biochemists. The document is based mainly on the recommendations of Australasian Association of Clinical Biochemists (AACB) Uncertainty of Measurement Working Group and is intended for all medical biochemistry laboratories in Croatia.
国际计量词汇-基本和通用概念及相关术语（VIM3，2.26 测量不确定度，JCGM 200:2012）将测量不确定度定义为一个非负参数，用于描述基于执行测量所获得的信息，对被测量赋值的量值分散性。临床实验室标准协会（CLSI）发布了一份非常详细的指南，其中描述了导致测量不确定度的来源，以及不同的计算方法（临床实验室测量不确定度的表达；经批准的指南，CLSI C51-A 2012）。已经发表了许多关于测量不确定度估计的其他国家和国际建议和原始科学论文。在克罗地亚，对于经过认证的医学实验室，测量不确定度的估计是强制性的。然而，由于目前没有国家建议，这些实验室中的每一个都在使用不同的方法进行测量不确定度估计。本文件的主要目的是描述测量不确定度估计的最低要求。通过这种方式，它将有助于在克罗地亚的实验室之间协调测量不确定度的估计、评估和报告。本建议由克罗地亚医学生物化学和实验室医学学会和克罗地亚医学生物化学师协会联合测量不确定度工作组发布。该文件主要基于澳大利亚临床生物化学家协会（AACB）不确定度工作组的建议，适用于克罗地亚所有医学生物化学实验室。
