a University of Eastern Finland, School of Medicine, Institute of Clinical Medicine , Department of Clinical Microbiology , Kuopio , Finland.
Hum Vaccin Immunother. 2018 Apr 3;14(4):807-814. doi: 10.1080/21645515.2017.1409315. Epub 2017 Dec 21.
Allergic diseases compose a serious challenge for modern societies. Their individual, medical and economical burden is large. As humans spend most of their time indoors, exposure to indoor allergens is a significant contributor to the development of allergic sensitization and respiratory allergies, such as allergic rhinoconjunctivitis and asthma. One important source of indoor allergens are pets, in particular cats and dogs. Allergens from these and other mammals spread effectively and they are encountered widely in public places. If patient education, allergen avoidance and pharmacotherapy do not suffice for controlling the symptoms of pet allergy, allergen immunotherapy can be a treatment option. Current information on allergen immunotherapy in pet allergy suggests that it can be effective in reducing allergic symptoms. However, the low number of high-quality randomized controlled trials of allergen immunotherapy in pet allergy warrants for further investigations.
过敏性疾病对现代社会构成了严重挑战。它们给个人、医疗和经济带来了沉重负担。由于人类大部分时间都在室内度过，因此接触室内过敏原是导致过敏敏感和呼吸道过敏（如过敏性鼻结膜炎和哮喘）的重要因素。室内过敏原的一个重要来源是宠物，特别是猫和狗。这些和其他哺乳动物的过敏原传播效果好，而且在公共场所广泛存在。如果患者教育、避免过敏原和药物治疗不足以控制宠物过敏症状，那么过敏原免疫疗法可以作为一种治疗选择。目前有关宠物过敏的过敏原免疫疗法的信息表明，它可以有效减轻过敏症状。然而，宠物过敏的过敏原免疫疗法高质量随机对照试验数量较少，需要进一步研究。
