Research Center for Food and Cosmetic Safety and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Kweishan, Taoyuan 333, Taiwan.
Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
Nutrients. 2017 Nov 30;9(12):1304. doi: 10.3390/nu9121304.
Flavonoids are bioactive phytochemicals that exhibit protective potential against cutaneous inflammation and photoaging. We selected eight flavonoid aglycones or glycosides to elucidate the chemistry behind their skin absorption capability through experimental and computational approaches. The skin delivery was conducted using nude mouse and pig skins mounted on an in vitro Franz cell assembly. The anti-inflammatory activity was examined using the O₂.
类黄酮是具有生物活性的植物化学成分,具有预防皮肤炎症和光老化的潜力。我们选择了 8 种类黄酮苷元或糖苷,通过实验和计算方法阐明了它们皮肤吸收能力背后的化学原理。使用安装在体外 Franz 细胞组件上的裸鼠和猪皮进行皮肤传递。使用 O₂ 来检查抗炎活性。