Health Sciences and Technology and Rehabilitation Sciencies Program, University of Brasilia, Centro Metropolitano, Conjunto A - Lote 01 - Ceilândia, Brasília, DF, 72220-900, Brazil.
Cancer Institute of Sao Paulo, Sao Paulo, Brazil.
Heart Fail Rev. 2018 Jan;23(1):73-89. doi: 10.1007/s10741-017-9658-8.
Recent literature suggests that resistance training (RT) improves peak oxygen uptake ([Formula: see text] peak), similarly to aerobic exercise (AE) in patients with heart failure (HF), but its effect on cardiac remodeling is controversial. Thus, we examined the effects of RT and AE on [Formula: see text] peak and cardiac remodeling in patients with heart failure (HF) via a systematic review and meta-analysis. MEDLINE, EMBASE, Cochrane Library and CINAHL, AMEDEO and PEDro databases search were extracted study characteristics, exercise type, and ventricular outcomes. The main outcomes were [Formula: see text] peak (ml kg min), LVEF (%) and LVEDV (mL). Fifty-nine RCTs were included. RT produced a greater increase in [Formula: see text] peak (3.57 ml kg min, P < 0.00001, I = 0%) compared to AE (2.63 ml kg min, P < 0.00001, I = 58%) while combined RT and AE produced a 2.48 ml kg min increase in [Formula: see text]; I = 69%) compared to control group. Comparison among the three forms of exercise revealed similar effects on [Formula: see text] peak (P = 0.84 and 1.00, respectively; I = 0%). AE was associated with a greater gain in LVEF (3.15%; P < 0.00001, I = 17%) compared to RT alone or combined exercise which produced similar gains compared to control groups. Subgroup analysis revealed that AE reduced LVEDV (- 10.21 ml; P = 0.007, I = 0%), while RT and combined RT and AE had no effect on LVEDV compared with control participants. RT results in a greater gain in [Formula: see text] peak, and induces no deleterious effects on cardiac function in HF patients.
近期文献表明，抗阻训练（RT）可提高峰值摄氧量（[Formula: see text] peak），与心力衰竭（HF）患者的有氧运动（AE）相似，但对心脏重构的影响存在争议。因此，我们通过系统评价和荟萃分析来检验 RT 和 AE 对心力衰竭（HF）患者[Formula: see text] peak 和心脏重构的影响。我们从 MEDLINE、EMBASE、Cochrane 图书馆和 CINAHL、AMEDEO 和 PEDro 数据库中提取研究特征、运动类型和心室结局。主要结局为[Formula: see text] peak（ml·kg·min）、左心室射血分数（LVEF）（%）和左心室舒张末期容积（LVEDV）（mL）。共纳入 59 项 RCT。与 AE（2.63 ml·kg·min，P<0.00001，I²=58%）相比，RT 可使[Formula: see text] peak 增加更多（3.57 ml·kg·min，P<0.00001，I²=0%），而 RT 和 AE 联合则使[Formula: see text] peak 增加 2.48 ml·kg·min；I²=69%）与对照组相比。三种运动形式之间的比较显示，在[Formula: see text] peak 方面的影响相似（P=0.84 和 1.00，分别；I²=0%）。AE 与单独 RT 或联合运动相比，可使 LVEF 增加更大（3.15%；P<0.00001，I²=17%），与对照组相比，单独 RT 和联合 RT 和 AE 产生相似的增益。亚组分析显示，AE 降低 LVEDV（-10.21 ml；P=0.007，I²=0%），而 RT 和联合 RT 和 AE 与对照组相比对 LVEDV 无影响。RT 可使[Formula: see text] peak 增加更多，并且对 HF 患者的心脏功能没有不良影响。
