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贲门失弛缓症的气囊扩张术:结果、并发症、成功率及长期随访

Pneumatic Balloon Dilatation for Achalasia Cardia: Outcome, Complications, Success, and Long-term Follow-up.

作者信息

J Gupta Sudhir, R Gaikwad Nitin, R Samarth Amol, R Gattewar Sonal

机构信息

Department of Gastroenterology, Government Medical College and Super Speciality Hospital, Nagpur, Maharashtra, India.

出版信息

Euroasian J Hepatogastroenterol. 2017 Jul-Dec;7(2):138-141. doi: 10.5005/jp-journals-10018-1234. Epub 2017 Sep 29.

Abstract

BACKGROUND

Achalasia is a chronic disease that can be managed with effective endoscopic modalities.

AIM

To evaluate the effectiveness of single setting of pneumatic balloon dilatation for achalasia and assess the long-term success and outcomes.

MATERIALS AND METHODS

This is a retrospective study of all achalasia patients who underwent pneumatic balloon dilatation at our institute. Patients who could be contacted were inquired regarding their symptoms and dysphagia-free interval after dilatation.

RESULTS

A total of 72 patients were enrolled. Out of this, 14 patients lost to follow-up. Mean age of 58 patients was 45.02 ± 16.51 years. Male:female ratio was 13:16. Mean predilatation Eckardt score was 7.16 ± 0.834. Type I achalasia was present in 10 (17.2%), type II in 44 (75.9%), type III in 4 (6.9%). Predilatation basal integrated relaxation pressure (IRP) was 28.14 ± 14.76 mm Hg. Postdilatation Eckardt score was 2.40 ± 1.67. Postdilatation dysphagia-free interval was 17.28 ± 6.70 months. A total of 9 patients (15.51%) failed to respond to first dilatation and 49 (84.48%) patients benefited from single setting of pneumatic dilatation. Esophageal perforation occurred in 2/58 (3.44%). We did not find any significant difference in gender distribution, age of presentation, duration of symptom, pre- and postdilatation Eckardt score, type of achalasia, and basal IRP on manometry between type of achalasia. Postdilatation dysphagia-free interval in type II achalasia (18.09 ± 5.976 months) was more than types I and III achalasia cardia (p = 0.066), which showed trend toward significance.

CONCLUSION

Pneumatic balloon dilatation of achalasia cardia is a highly effective endoscopic procedure with minimal complications and mortality. Even the single setting of dilatation can have long-lasting dysphagia-free interval. Gupta SJ, Gaikwad NR, Samarth AR, Gattewar SR. Pneumatic Balloon Dilatation for Achalasia Cardia: Outcome, Complications, Success, and Long-term Follow-up. Euroasian J Hepato-Gastroenterol 2017;7(2):138-141.

摘要

背景

贲门失弛缓症是一种可通过有效的内镜治疗方法进行管理的慢性疾病。

目的

评估单次气囊扩张治疗贲门失弛缓症的有效性,并评估长期成功率及结果。

材料与方法

这是一项对在我院接受气囊扩张治疗的所有贲门失弛缓症患者的回顾性研究。对能够联系上的患者询问其症状及扩张后的无吞咽困难间期。

结果

共纳入72例患者。其中,14例失访。58例患者的平均年龄为45.02±16.51岁。男女比例为13:16。扩张前埃卡德特评分平均为7.16±0.834。I型贲门失弛缓症10例(17.2%),II型44例(75.9%),III型4例(6.9%)。扩张前基础综合松弛压(IRP)为28.14±14.76 mmHg。扩张后埃卡德特评分2.40±1.67。扩张后无吞咽困难间期为17.28±6.70个月。共有9例患者(15.51%)对首次扩张无反应,49例(84.48%)患者从单次气囊扩张中获益。2/58例(3.44%)发生食管穿孔。我们未发现贲门失弛缓症类型之间在性别分布、发病年龄、症状持续时间、扩张前后埃卡德特评分、贲门失弛缓症类型及测压时基础IRP方面存在任何显著差异。II型贲门失弛缓症扩张后的无吞咽困难间期(18.09±5.976个月)长于I型和III型贲门失弛缓症(p = 0.066),有显著趋势。

结论

贲门失弛缓症的气囊扩张是一种高效的内镜手术,并发症和死亡率极低。即使是单次扩张也能有持久的无吞咽困难间期。古普塔SJ、盖克瓦德NR、萨马尔思AR、加特瓦尔SR。贲门失弛缓症的气囊扩张:结果、并发症、成功率及长期随访。《欧亚肝脏胃肠病学杂志》2017年;7(2):138 - 141。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1eae/5670256/e354ec9f3b79/ejohg-07-138-g001.jpg

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