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胸腰椎结核的外科治疗:一项多中心回顾性研究。

Surgical Treatment of Thoracic Spinal Tuberculosis: A Multicenter Retrospective Study.

机构信息

Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.

Department of Orthopaedics, The Lanzhou general Hospital, Lanzhou Military Command of CPLA, Lanzhou, China.

出版信息

World Neurosurg. 2018 Feb;110:e842-e850. doi: 10.1016/j.wneu.2017.11.126. Epub 2017 Dec 6.

Abstract

OBJECTIVE

The aim of the present multicenter, retrospective study was to assess the safety and effectiveness of different surgery strategies for the treatment of thoracic tuberculosis and to provide a reference for surgical treatment of thoracic tuberculosis.

MATERIALS AND METHODS

This study reviewed 394 patients with thoracic tuberculosis who were treated in 6 institutions between January 2000 and January 2015. There were 208 men and 186 women with an average age of 34.92 ± 13.14 years (range 5-76 years). A total of 73 patients underwent one-stage anterior surgery (group A); 84 underwent an anterior combined posterior surgery (group B); and 237 underwent one-stage posterior surgery (group C). Clinical outcome, laboratory indexes, and radiologic results were analyzed to observe the advantage of posterior approach surgery.

RESULTS

All cases were followed up for about 26-60 months (average of 37 months). At the last follow-up, all patients reached bone fusion, pain relief, and neurologic recovery. There were significant differences before and after treatment in terms of the visual analog scale and Oswestry Disability Index scores (P < 0.05). Posterior approach significantly improved kyphosis (P < 0.05).

CONCLUSIONS

Posterior fixation is superior to anterior fixation in the correction of kyphosis and maintenance of spinal stability. One-stage posterior surgery can achieve the same efficacy as anterior-only or combined surgery, with less trauma, less blood loss, and shorter operative times. However, for wide lesions or paraspinal abscesses, severe bone destruction, and anterior and middle column defects that are too large after debridement to require long segment bone grafting, the anterior combined posterior approach is indispensable.

摘要

目的

本多中心回顾性研究旨在评估不同手术策略治疗胸壁结核的安全性和有效性,并为胸壁结核的手术治疗提供参考。

材料与方法

本研究回顾性分析了 2000 年 1 月至 2015 年 1 月期间 6 家机构收治的 394 例胸壁结核患者。其中男 208 例,女 186 例,平均年龄 34.92±13.14 岁(5-76 岁)。73 例患者行一期前路手术(A 组);84 例行前路联合后路手术(B 组);237 例行一期后路手术(C 组)。分析临床疗效、实验室指标和影像学结果,观察后路手术的优势。

结果

所有患者均获随访,随访时间 26-60 个月,平均 37 个月。末次随访时,所有患者均达到骨融合、疼痛缓解和神经功能恢复。视觉模拟评分和 Oswestry 功能障碍指数评分治疗前后比较差异有统计学意义(P<0.05)。后路手术明显改善后凸畸形(P<0.05)。

结论

后路固定在矫正后凸畸形和维持脊柱稳定性方面优于前路固定。一期后路手术与前路或前路联合手术具有相同的疗效,创伤小、出血量少、手术时间短。但对于广泛病变或椎旁脓肿、严重骨质破坏、清创后前中柱缺损过大需长节段植骨者,前路联合后路是必不可少的。

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