Reif J S, Pearce N E, Fraser J
Department of Environmental Health, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, Colorado.
Scand J Work Environ Health. 1989 Feb;15(1):24-9. doi: 10.5271/sjweh.1886.
The study reports a series of case-referent studies based on the New Zealand Cancer Register and involving 19,904 male cancer patients aged 20 years or more at the time of registration during the period 1980-1984. For each cancer site, the registrations for the remaining sites formed the reference group. An increased risk for lung (OR 1.30, 95% CI 1.06-1.58) and laryngeal (OR 2.01, 95% CI 1.19-3.39) cancer was found among meatworkers. It was confined to men aged less than 65 years at registration. The risk for soft-tissue sarcoma was elevated (OR 1.90, 95% CI 0.90-4.02). The risk estimate for all types of leukemia was elevated moderately (OR 1.45, 95% CI 0.90-2.31), but cell type-specific analyses revealed a greater effect for acute myeloid leukemia (OR 2.12, 95% CI 1.09-4.12). This study adds to the evidence that employment as a meatworker is associated with increased risk for several forms of cancer.
该研究报告了一系列基于新西兰癌症登记处的病例对照研究,涉及1980年至1984年期间登记时年龄在20岁及以上的19904名男性癌症患者。对于每个癌症部位,其余部位的登记病例构成对照组。肉类加工工人中肺癌(比值比1.30,95%置信区间1.06 - 1.58)和喉癌(比值比2.01,95%置信区间1.19 - 3.39)的风险增加。这种情况仅限于登记时年龄小于65岁的男性。软组织肉瘤的风险升高(比值比1.90,95%置信区间0.90 - 4.02)。所有类型白血病的风险估计值适度升高(比值比1.45,95%置信区间0.90 - 2.31),但细胞类型特异性分析显示急性髓细胞白血病的影响更大(比值比2.12,95%置信区间1.09 - 4.12)。这项研究进一步证明,从事肉类加工工作与多种癌症风险增加有关。