帕金森病开期和关期的诱发电位、反应时间及认知表现
Evoked potentials, reaction time and cognitive performance in on and off phases of Parkinson's disease.
作者信息
Starkstein S E, Esteguy M, Berthier M L, Garcia H, Leiguarda R
机构信息
Institute of Neurological Research, Dr. Paul Carrea, Buenos Aires, Argentina.
出版信息
J Neurol Neurosurg Psychiatry. 1989 Mar;52(3):338-40. doi: 10.1136/jnnp.52.3.338.
Abstract
Seven patients with Parkinson's disease and severe motor fluctuations were studied with event-related potentials, reaction and movement times and neuropsychological tests while in "off" and "on" phases. While there was a significant decrement in the P300 latency of the event-related potentials and in the duration of movement time in the "on" phase, no significant differences between on and off phases were observed in reaction time and neuropsychological tasks.
摘要
对7例患有帕金森病且存在严重运动波动的患者，在“关”期和“开”期进行了事件相关电位、反应时间、运动时间及神经心理学测试。虽然在“开”期事件相关电位的P300潜伏期及运动时间持续时间有显著缩短，但在反应时间和神经心理学任务方面，“开”期和“关”期未观察到显著差异。
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