Starkstein S E, Esteguy M, Berthier M L, Garcia H, Leiguarda R
Institute of Neurological Research, Dr. Paul Carrea, Buenos Aires, Argentina.
J Neurol Neurosurg Psychiatry. 1989 Mar;52(3):338-40. doi: 10.1136/jnnp.52.3.338.
Seven patients with Parkinson's disease and severe motor fluctuations were studied with event-related potentials, reaction and movement times and neuropsychological tests while in "off" and "on" phases. While there was a significant decrement in the P300 latency of the event-related potentials and in the duration of movement time in the "on" phase, no significant differences between on and off phases were observed in reaction time and neuropsychological tasks.
对7例患有帕金森病且存在严重运动波动的患者，在“关”期和“开”期进行了事件相关电位、反应时间、运动时间及神经心理学测试。虽然在“开”期事件相关电位的P300潜伏期及运动时间持续时间有显著缩短，但在反应时间和神经心理学任务方面，“开”期和“关”期未观察到显著差异。
