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子宫内膜异位症外科治疗的建议——第1部分:卵巢子宫内膜异位囊肿

Recommendations for the surgical treatment of endometriosis-part 1: ovarian endometrioma.

作者信息

Saridogan Ertan, Becker Christian M, Feki Anis, Grimbizis Grigoris F, Hummelshoj Lone, Keckstein Joerg, Nisolle Michelle, Tanos Vasilios, Ulrich Uwe A, Vermeulen Nathalie, De Wilde Rudy Leon

机构信息

Institute for Women's Health, University College Hospital, Reproductive Medicine Unit, Elizabeth Garrett Anderson Wing, London, NW1 2BU UK.

Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Endometriosis CaRe Centre, John Radcliffe Hospital, Women's Centre, Oxford, OX3 9DU UK.

出版信息

Gynecol Surg. 2017;14(1):27. doi: 10.1186/s10397-017-1029-x. Epub 2017 Dec 19.

Abstract

STUDY QUESTION

What does this document on the surgical treatment of endometriosis jointly prepared by the European Society for Gynaecological Endoscopy (ESGE), ESHRE, and the World Endometriosis Society (WES) provide?

SUMMARY ANSWER

This document provides recommendations covering technical aspects of different methods of surgery for endometriomas in women of reproductive age.

WHAT IS ALREADY KNOWN

Endometriomas (ovarian endometriotic cysts) are a commonly diagnosed form of endometriosis, owing to the relative ease and accuracy of ultrasound diagnosis. They frequently present a clinical dilemma as to whether and how to treat them when found during imaging or incidentally during surgery. Previously published guidelines have provided recommendations based on the best available evidence, but without technical details on the management of endometriosis.

STUDY DESIGN SIZE AND DURATION

A working group of ESGE, ESHRE and WES collaborated on writing recommendations on the practical aspects of endometrioma surgery.

PARTICIPANTS/MATERIALS SETTING AND METHODS: This document focused on endometrioma surgery. Further documents in this series will provide recommendations for surgery of deep and peritoneal endometriosis.

MAIN RESULTS AND THE ROLE OF CHANCE

The document presents general recommendations for surgery of endometrioma and specific recommendations for cystectomy, ablation by laser or by plasma energy, electrocoagulation and a combination of these techniques applied together or with an interval between them.

LIMITATIONS AND REASONS FOR CAUTION

Owing to the limited evidence available, recommendations are mostly based on clinical expertise.

WIDER IMPLICATIONS OF THE FINDINGS

These recommendations complement previous guidelines on the management of endometriosis.

STUDY FUNDING/COMPETING INTERESTS: The meetings of the working group were funded by ESGE, ESHRE and WES. CB declares to be a member of the independent data monitoring committee for a clinical study by ObsEva and receiving research grants from Bayer, Roche Diagnostics, MDNA Life Sciences and Volition. ES received honoraria for provision of training to healthcare professionals from Ethicon, Olympus and Gedeon Richter. The other authors declare that they have no conflict of interest.

摘要

研究问题

欧洲妇科内镜学会(ESGE)、欧洲人类生殖与胚胎学会(ESHRE)以及世界子宫内膜异位症学会(WES)联合编写的这份关于子宫内膜异位症手术治疗的文件提供了什么内容?

总结答案

本文件提供了涵盖育龄期女性卵巢巧克力囊肿(子宫内膜异位囊肿)不同手术方法技术方面的建议。

已知信息

卵巢巧克力囊肿(子宫内膜异位囊肿)是一种常见的子宫内膜异位症诊断形式,这是由于超声诊断相对容易且准确。当在影像学检查中发现或手术中偶然发现时,对于是否以及如何治疗它们,常常会出现临床困境。先前发布的指南已根据现有最佳证据提供了建议,但没有关于子宫内膜异位症管理的技术细节。

研究设计、规模和持续时间:ESGE、ESHRE和WES的一个工作组合作编写了关于卵巢巧克力囊肿手术实际操作方面的建议。

参与者/材料、设置和方法:本文件聚焦于卵巢巧克力囊肿手术。本系列的其他文件将提供深部和腹膜子宫内膜异位症手术的建议。

主要结果及机遇的作用

该文件提出了卵巢巧克力囊肿手术的一般建议以及囊肿切除术、激光或等离子体能量消融、电凝术以及这些技术联合应用或间隔应用的具体建议。

局限性及谨慎原因

由于现有证据有限,建议大多基于临床专业知识。

研究结果的更广泛影响

这些建议补充了先前关于子宫内膜异位症管理的指南。

研究资金/利益冲突:工作组会议由ESGE、ESHRE和WES资助。CB宣称是ObsEva一项临床研究独立数据监测委员会的成员,并从拜耳、罗氏诊断、MDNA生命科学和Volition获得研究资助。ES因向医疗保健专业人员提供培训而从爱惜康、奥林巴斯和吉德昂·里奇特获得酬金。其他作者宣称他们没有利益冲突。

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本文引用的文献

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Blood biomarkers for the non-invasive diagnosis of endometriosis.用于子宫内膜异位症无创诊断的血液生物标志物。
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