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四大发展阶段焦虑障碍的发生率、复发率和共病情况。

Incidence, recurrence and comorbidity of anxiety disorders in four major developmental stages.

机构信息

Department of Psychology, University of Roehampton, Whitelands College, Holybourne Avenue, London SW15 4JD, UK.

Oregon Research Institute, 1776 Millrace Drive Eugene, OR 97403-1983, USA.

出版信息

J Affect Disord. 2018 Mar 1;228:248-253. doi: 10.1016/j.jad.2017.12.014. Epub 2017 Dec 8.

Abstract

BACKGROUND

Anxiety disorders are common in childhood, adolescence, and adulthood, and frequently comorbid with other mental disorders.

OBJECTIVE

The main aim of the present study was to examine the incidence, recurrence and comorbidity rates of anxiety disorders across four developmental periods, namely, during childhood (5 - 12.9 years), adolescence (13 - 17.9 years), emerging adulthood (18 - 23.9 years), and adulthood (24 - 30 years).

METHOD

Eight hundred and sixteen participants from a large community sample were interviewed twice during adolescence, at age 24, and at age 30. They completed self-report measures of psychosocial functioning and semi-structured diagnostic interviews during adolescence and adulthood.

RESULTS

The result showed first incidence of anxiety disorders to be significantly higher in childhood and adulthood than in adolescence and emerging adulthood. Female gender was associated with first incidence, but not with recurrence. Significant comorbidity was found between anxiety disorders and major depressive disorder (MDD) across the four developmental periods. The comorbidity between anxiety and substance use disorders (SUD) was significant in childhood, emerging adulthood and adulthood, but not in adolescence. The presence of anxiety disorders during childhood and adolescence significantly increased the probability of having an anxiety disorder during emerging adulthood.

LIMITATIONS

The participants are ethically and geographically homogenous.

CONCLUSION

Incidence and recurrence rates of anxiety disorders differed across four diverse developmental periods. The magnitude of comorbidity between anxiety disorders and MDD was comparable across periods.

摘要

背景

焦虑障碍在儿童期、青少年期和成年期很常见,并且经常与其他精神障碍共病。

目的

本研究的主要目的是在四个发育阶段(儿童期(5-12.9 岁)、青少年期(13-17.9 岁)、成年早期(18-23.9 岁)和成年期(24-30 岁))中检查焦虑障碍的发生率、复发率和共病率。

方法

816 名来自大型社区样本的参与者在青少年期(24 岁和 30 岁)两次接受访谈。他们在青少年和成年期完成了心理社会功能的自我报告测量和半结构化诊断访谈。

结果

结果显示,焦虑障碍的首次发病率在儿童期和成年期明显高于青少年和成年早期。女性性别与首次发病有关,但与复发无关。在四个发育阶段都发现焦虑障碍与重性抑郁障碍(MDD)之间存在显著的共病。焦虑和物质使用障碍(SUD)之间的共病在儿童期、成年早期和成年期显著,但在青少年期不显著。儿童期和青少年期的焦虑障碍存在显著增加了成年早期出现焦虑障碍的可能性。

局限性

参与者在伦理和地理上是同质的。

结论

焦虑障碍的发生率和复发率在四个不同的发育阶段有所不同。焦虑障碍和 MDD 之间的共病程度在各阶段相当。

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