Lewinsohn P M, Rohde P, Seeley J R, Klein D N
Oregon Research Institute, Eugene 97403-1983, USA.
J Am Acad Child Adolesc Psychiatry. 1997 Dec;36(12):1752-9. doi: 10.1097/00004583-199712000-00024.
To examine the occurrence of elevated personality disorder (PD) dimensional scores in a community sample of young adults as a function of the occurrence of Axis I disorders through age 18 years.
299 individuals who had been interviewed regarding Axis I disorders twice while in adolescence (first when 14 through 18 years of age) were carefully assessed regarding Axis I and II psychopathology at age 24.
The prevalence of PD diagnoses was relatively low (3.8% in participants with a history of Axis I versus 1.7% in participants with no Axis I history). The occurrence of all four Axis I diagnostic categories (major depression, anxiety disorders, disruptive behavior disorders, substance use disorders) in childhood and adolescence was associated with elevated PD dimensional scores. The likelihood of elevated PD dimensional scores increased as a function of the number of Axis I disorders. Elevated PD scores were significantly associated with a negative course of major depression.
Although the rates of PDs were low, the findings suggest a substantial degree of association between early-onset Axis I disorders and Axis II psychopathology in young adulthood. More research is needed to develop assessment and treatment recommendations addressing the early manifestations of PDs.
研究在一个年轻成人社区样本中,人格障碍(PD)维度评分升高的发生率与18岁之前轴I障碍发生率之间的关系。
对299名在青春期时就轴I障碍接受过两次访谈(第一次在14至18岁时)的个体,在其24岁时对轴I和轴II精神病理学进行了仔细评估。
PD诊断的患病率相对较低(有轴I病史的参与者中为3.8%,无轴I病史的参与者中为1.7%)。童年和青春期所有四个轴I诊断类别(重度抑郁症、焦虑症、破坏性行为障碍、物质使用障碍)的发生都与PD维度评分升高有关。PD维度评分升高的可能性随着轴I障碍的数量增加而增加。PD评分升高与重度抑郁症的不良病程显著相关。
虽然PD的发生率较低,但研究结果表明,早期发作的轴I障碍与年轻成年期的轴II精神病理学之间存在相当程度的关联。需要更多的研究来制定针对PD早期表现的评估和治疗建议。