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环丙沙星诱发的血尿。

Ciprofloxacin-induced hematuria.

作者信息

Garlando F, Täuber M G, Joos B, Oelz O, Lüthy R

出版信息

Infection. 1985 Jul-Aug;13(4):177-8. doi: 10.1007/BF01642807.

DOI:10.1007/BF01642807
PMID:2931381
Abstract

We used ciprofloxacin, a quinolone-derivative, to treat a lung infection due to Pseudomonas aeruginosa in an adult cystic fibrosis patient. On three different occasions the use of ciprofloxacin was associated with the development of an asymptomatic hematuria with red blood cell casts. The mechanism responsible for this hematuria is presently unknown, but clinicians should be aware of this potential adverse effect of ciprofloxacin.

摘要

我们使用喹诺酮衍生物环丙沙星,治疗一名成年囊性纤维化患者因铜绿假单胞菌引起的肺部感染。在三个不同的时间段,使用环丙沙星均出现了伴有红细胞管型的无症状血尿。目前尚不清楚导致这种血尿的机制,但临床医生应注意环丙沙星的这一潜在不良反应。

相似文献

1
Ciprofloxacin-induced hematuria.环丙沙星诱发的血尿。
Infection. 1985 Jul-Aug;13(4):177-8. doi: 10.1007/BF01642807.
2
In-vitro activity of ciprofloxacin and other antibacterial agents against Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients.环丙沙星及其他抗菌药物对囊性纤维化患者铜绿假单胞菌和洋葱伯克霍尔德菌的体外活性。
J Antimicrob Chemother. 1985 Jun;15(6):679-84. doi: 10.1093/jac/15.6.679.
3
Ciprofloxacin pharmacokinetics in patients with cystic fibrosis.
Infection. 1986 Jan-Feb;14(1):17-21. doi: 10.1007/BF01644804.
4
Oral ciprofloxacin in the treatment of pseudomonas exacerbations of paediatric cystic fibrosis: clinical efficacy and safety evaluation using magnetic resonance image scanning.口服环丙沙星治疗小儿囊性纤维化假单胞菌感染加重:使用磁共振成像扫描进行临床疗效和安全性评估
J Int Med Res. 1998 Dec;26(6):304-12. doi: 10.1177/030006059802600604.
5
Safety and pharmacokinetics of ciprofloxacin dry powder for inhalation in cystic fibrosis: a phase I, randomized, single-dose, dose-escalation study.环丙沙星吸入用干粉在囊性纤维化患者中的安全性和药代动力学:一项I期随机单剂量剂量递增研究。
J Aerosol Med Pulm Drug Deliv. 2015 Apr;28(2):106-15. doi: 10.1089/jamp.2013.1056. Epub 2014 Jul 22.
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Sequential ciprofloxacin therapy in pediatric cystic fibrosis: comparative study vs. ceftazidime/tobramycin in the treatment of acute pulmonary exacerbations. The Cystic Fibrosis Study Group.儿童囊性纤维化的环丙沙星序贯疗法:与头孢他啶/妥布霉素治疗急性肺部加重期的对比研究。囊性纤维化研究组
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Oral ciprofloxacin therapy of infections due to Pseudomonas aeruginosa.口服环丙沙星治疗铜绿假单胞菌感染
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Ciprofloxacin in cystic fibrosis.环丙沙星与囊性纤维化
Lancet. 1986 May 10;1(8489):1103. doi: 10.1016/s0140-6736(86)91374-7.
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Ciprofloxacin: comparative data in cystic fibrosis.环丙沙星:囊性纤维化的对比数据。
Am J Med. 1987 Apr 27;82(4A):185-8.
10
Ciprofloxacin monotherapy for acute pulmonary exacerbations of cystic fibrosis.环丙沙星单药治疗囊性纤维化急性肺部加重期
Am J Med. 1987 Apr 27;82(4A):174-9.

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Adverse reactions to fluoroquinolones in the Nigerian population: an audit of reports submitted to the National Pharmacovigilance Centre from 2004 to 2016.尼日利亚人群中氟喹诺酮类药物的不良反应:对2004年至2016年提交给国家药物警戒中心报告的审核
Pharmacol Res Perspect. 2017 Feb 14;5(2):e00297. doi: 10.1002/prp2.297. eCollection 2017 Apr.
2
Detection of Ciprofloxacin in Urine through Sensitized Lanthanide Luminescence.通过敏化镧系元素发光检测尿液中的环丙沙星。
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Tolerability of fluoroquinolone antibiotics. Past, present and future.

本文引用的文献

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Dose- and sex-independent disposition of ciprofloxacin.
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Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.环丙沙星(拜奥9867)、诺氟沙星、吡哌酸和萘啶酸的比较活性。
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Comparison of high-pressure liquid chromatography and bioassay for determination of ciprofloxacin in serum and urine.高压液相色谱法与生物测定法测定血清和尿液中环丙沙星的比较。
氟喹诺酮类抗生素的耐受性:过去、现在与未来
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Investigation on renal tolerability of ciprofloxacin with tests based on monoclonal antibodies.基于单克隆抗体检测的环丙沙星肾脏耐受性研究。
Infection. 1988;16 Suppl 1:S69-75. doi: 10.1007/BF01650513.
5
Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.环丙沙星:抗菌活性、药代动力学特性及治疗用途综述
Drugs. 1988 Apr;35(4):373-447. doi: 10.2165/00003495-198835040-00003.
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Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients.比较环丙沙星联合奈替米星与哌拉西林联合奈替米星对中性粒细胞减少患者发热进行经验性治疗的随机试验。
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Quinolone antimicrobial agents: adverse effects and bacterial resistance.喹诺酮类抗菌药物:不良反应与细菌耐药性。
Eur J Clin Microbiol Infect Dis. 1989 Dec;8(12):1080-92. doi: 10.1007/BF01975175.
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Clinical pharmacokinetics of ciprofloxacin.
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Clinical features and management of adverse effects of quinolone antibacterials.
Drug Saf. 1991 Jan-Feb;6(1):8-27. doi: 10.2165/00002018-199106010-00002.
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Ciprofloxacin in typhoid fever.环丙沙星治疗伤寒热。
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Antimicrob Agents Chemother. 1985 Mar;27(3):353-6. doi: 10.1128/AAC.27.3.353.
4
The nephrotoxicity of antimicrobial agents (third of three parts).抗菌药物的肾毒性(三部分之三)
N Engl J Med. 1977 Apr 7;296(14):784-7. doi: 10.1056/NEJM197704072961404.