环丙沙星（拜奥9867）、诺氟沙星、吡哌酸和萘啶酸的比较活性。
Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.
作者信息
Muytjens H L, van der Ros-van de Repe J, van Veldhuizen G
出版信息
Antimicrob Agents Chemother. 1983 Aug;24(2):302-4. doi: 10.1128/AAC.24.2.302.
Abstract
An agar dilution method was used to measure the minimal inhibitory concentrations of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid against 496 clinical isolates. Ciprofloxacin and norfloxacin were active against all species tested (90% minimal inhibitory concentrations less than or equal to 8 micrograms/ml), although ciprofloxacin was somewhat more active, e.g., against gram-positive cocci. Pipemidic acid and nalidixic acid were active against most of the members of the Enterobacteriaceae, but Klebsiella species and Providencia stuartii were only inhibited by a high concentration of nalidixic acid.
摘要
采用琼脂稀释法测定环丙沙星（拜奥9867）、诺氟沙星、吡哌酸和萘啶酸对496株临床分离菌的最低抑菌浓度。环丙沙星和诺氟沙星对所有测试菌种均有活性（90%的最低抑菌浓度小于或等于8微克/毫升），尽管环丙沙星的活性稍强，例如对革兰氏阳性球菌。吡哌酸和萘啶酸对大多数肠杆菌科菌属有活性，但克雷伯菌属和斯氏普罗威登斯菌仅在高浓度萘啶酸作用下才被抑制。
相似文献
1
Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.环丙沙星（拜奥9867）、诺氟沙星、吡哌酸和萘啶酸的比较活性。
Antimicrob Agents Chemother. 1983 Aug;24(2):302-4. doi: 10.1128/AAC.24.2.302.
2
In vitro activities of ciprofloxacin, norfloxacin, pipemidic acid, cinoxacin, and nalidixic acid against Chlamydia trachomatis.环丙沙星、诺氟沙星、吡哌酸、西诺沙星和萘啶酸对沙眼衣原体的体外活性
Antimicrob Agents Chemother. 1984 Jan;25(1):123-4. doi: 10.1128/AAC.25.1.123.
3
Ciprofloxacin (BAY O 9867). Comparative in vitro activity study.环丙沙星（BAY O 9867）。体外活性比较研究。
Microbiol Esp. 1984 Jul-Dec;37(3-4):73-9.
4
In vitro activity of norfloxacin in synthetic media and human urine compared to that of cinnoxacin, nalidixic acid and pipemidic acid.与西诺沙星、萘啶酸和吡哌酸相比，诺氟沙星在合成培养基和人尿中的体外活性。
Methods Find Exp Clin Pharmacol. 1983 Dec;5(10):731-4.
5
In vitro activity of ciprofloxacin (Bay o 9867).环丙沙星（拜耳o 9867）的体外活性。
Antimicrob Agents Chemother. 1983 Oct;24(4):568-74. doi: 10.1128/AAC.24.4.568.
6
Antibacterial activities of ciprofloxacin, norfloxacin, oxolinic acid, cinoxacin, and nalidixic acid.环丙沙星、诺氟沙星、恶喹酸、西诺沙星和萘啶酸的抗菌活性。
Antimicrob Agents Chemother. 1984 May;25(5):633-7. doi: 10.1128/AAC.25.5.633.
7
In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.新型喹啉衍生物Bay 09867与其他抗菌药物的体外活性比较。
Antimicrob Agents Chemother. 1983 Apr;23(4):559-64. doi: 10.1128/AAC.23.4.559.
8
In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid.环丙沙星、诺氟沙星和萘啶酸的体外活性。
Eur J Clin Microbiol. 1983 Apr;2(2):111-5. doi: 10.1007/BF02001575.
9
Incomplete cross-resistance of nalidixic and pipemidic acid-resistant variants of Serratia marcescens against ciprofloxacin, enoxacin, and norfloxacin.粘质沙雷氏菌对萘啶酸和吡哌酸耐药的变异株对环丙沙星、依诺沙星和诺氟沙星存在不完全交叉耐药性。
Chemotherapy. 1985;31(1):34-9. doi: 10.1159/000238311.
引用本文的文献
1
Aqueous penetration of orally administered ciprofloxacin in humans.口服环丙沙星在人体中的水渗透情况。
Int Ophthalmol. 1994;18(4):221-4. doi: 10.1007/BF00951801.
2
Effect of inoculum, pH, and medium on the activity of ciprofloxacin against anaerobic bacteria.接种量、pH值和培养基对环丙沙星抗厌氧菌活性的影响。
Antimicrob Agents Chemother. 1984 Mar;25(3):342-3. doi: 10.1128/AAC.25.3.342.
3
Penetration of pefloxacin into cerebrospinal fluid of patients with meningitis.培氟沙星在脑膜炎患者脑脊液中的穿透情况。
Antimicrob Agents Chemother. 1984 Sep;26(3):289-91. doi: 10.1128/AAC.26.3.289.
4
Ciprofloxacin penetration into extravascular spaces in a rabbit model.环丙沙星在兔模型中向血管外间隙的渗透情况。
Antimicrob Agents Chemother. 1984 Dec;26(6):935-6. doi: 10.1128/AAC.26.6.935.
5
In vitro susceptibility of anaerobic bacteria to ciprofloxacin (Bay o 9867).厌氧菌对环丙沙星（拜奥9867）的体外敏感性
Antimicrob Agents Chemother. 1984 Nov;26(5):785-6. doi: 10.1128/AAC.26.5.785.
6
In vitro activity of ciprofloxacin against aerobic gram-negative bacteria.环丙沙星对需氧革兰氏阴性菌的体外活性。
Antimicrob Agents Chemother. 1984 Oct;26(4):597-8. doi: 10.1128/AAC.26.4.597.
7
Susceptibility of Legionella spp. to quinolone derivatives and related organic acids.军团菌属对喹诺酮衍生物及相关有机酸的敏感性。
Eur J Clin Microbiol. 1984 Aug;3(4):373. doi: 10.1007/BF01977502.
8
Amifloxacin activity against well-defined gentamicin-resistant, gram-negative bacteria.阿米氟沙星对明确的耐庆大霉素革兰氏阴性菌的活性。
Antimicrob Agents Chemother. 1984 Nov;26(5):781-4. doi: 10.1128/AAC.26.5.781.
9
In vitro activity of ciprofloxacin, azthreonam and ceftazidime against Serratia marcescens and Pseudomonas aeruginosa.环丙沙星、氨曲南和头孢他啶对粘质沙雷氏菌和铜绿假单胞菌的体外活性。
Eur J Clin Microbiol. 1984 Aug;3(4):368-9. doi: 10.1007/BF01977498.
10
Selective decontamination of the digestive tract by pipemidic acid.吡哌酸对消化道的选择性去污染
Antimicrob Agents Chemother. 1983 Dec;24(6):902-4. doi: 10.1128/AAC.24.6.902.
本文引用的文献
1
Comparative activities of 13 beta-lactam antibiotics.13种β-内酰胺类抗生素的比较活性
Antimicrob Agents Chemother. 1982 Jun;21(6):925-34. doi: 10.1128/AAC.21.6.925.
2
Norfloxacin and the antibacterial gamma pyridone beta carboxylic acids.诺氟沙星与抗菌性γ-吡啶酮β-羧酸类化合物。
J Antimicrob Chemother. 1982 Jul;10(1):25-30. doi: 10.1093/jac/10.1.25.
3
In vitro activity of MK-0366 against clinical urinary pathogens including gentamicin-resistant Pseudomonas aeruginosa.MK-0366对包括耐庆大霉素铜绿假单胞菌在内的临床尿路病原体的体外活性。
Antimicrob Agents Chemother. 1982 Apr;21(4):670-2. doi: 10.1128/AAC.21.4.670.
Zotero 插件