Al-Rifai Asma'a, Aqel Ahmad, Al-Warhi Tarfah, Wabaidur Saikh M, Al-Othman Zeid A, Badjah-Hadj-Ahmed A Yacine
Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Evid Based Complement Alternat Med. 2017;2017:5694305. doi: 10.1155/2017/5694305. Epub 2017 Nov 26.
Abdallah & Sa'ad and Desr. are commonly used in the Saudi Arabia folk medicine. They are potent in treating the ulcers and skin diseases. The lack of information about their biological activities led us to investigate the possible biological activities by determination of antibacterial and antioxidant activities of total ethanolic extracts and various fractions. Total flavonoid contents of the plants were determined by colorimetric method while total phenols were determined by using Folin-Ciocalteu method. antibacterial activity was studied against , , and , and the total antioxidant capacity was evaluated by radical scavenging method. IC were found to be 21.81, 17.62, and 3.31 g/mL for , , and vitamin C, respectively, while the lowest MIC value of 0.25 mg/mL was recorded with extract against Around 21 compounds are tentatively elucidated from both plants using rapid, simple, and high-resolution analytical technique for chemical profiling of natural compounds by direct analysis in real-time of flight-mass spectrometry, of which 17 were not isolated or reported previously.
阿卜杜拉和萨阿德以及德斯尔常用于沙特阿拉伯民间医学。它们在治疗溃疡和皮肤病方面效果显著。由于缺乏关于其生物活性的信息，我们通过测定总乙醇提取物和各种馏分的抗菌和抗氧化活性来研究其可能的生物活性。采用比色法测定植物中的总黄酮含量，采用福林-西奥尔特法测定总酚含量。研究了对[具体细菌名称未给出]、[具体细菌名称未给出]和[具体细菌名称未给出]的抗菌活性，并通过自由基清除法评估总抗氧化能力。发现[具体提取物未给出]、[具体提取物未给出]和维生素C的半数抑制浓度（IC）分别为21.81、17.62和3.31μg/mL，而[具体提取物未给出]提取物对[具体细菌名称未给出]的最低最低抑菌浓度（MIC）值记录为0.25mg/mL。使用快速、简单且高分辨率的分析技术，通过飞行时间质谱实时直接分析对两种植物中的天然化合物进行化学剖析，初步鉴定出约21种化合物，其中17种以前未被分离或报道过。
