Dimitriou Nefeli, Nasios Grigorios, Nousia Anastasia, Anyfantis Emmanouil, Messinis Lambros, Dimakopoulos Georgios, El-Wahsh Sarah, Bakirtzis Christos, Kostadima Vasiliki, Konitsiotis Spiridon
Department of Speech and Language Therapy, University of Ioannina, Ioannina, Greece.
Department of Speech and Language Therapy, University of Peloponnese, Kalamata 24100, Greece.
Arch Clin Neuropsychol. 2025 Apr 27;40(3):635-641. doi: 10.1093/arclin/acae015.
The aim of the present study was to validate the Communication and Language Assessment questionnaire for persons with Multiple Sclerosis (CLAMS) into the Greek language.
106 Persons with Multiple Sclerosis (PwMS) and 51 healthy controls (HCs) participated in this study. We evaluated patients' cognitive abilities with the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS). All PwMS completed the CLAMS and three additional questionnaires (Speech Pathology-Specific Questionnaire for persons with Multiple Sclerosis, SMS; Stroke and Aphasia Quality of Life Scale-39, SAQOL-39; the Beck Depression Inventory Fast Screen, BDI-FS), and all HCs filled in the CLAMS.
The internal consistency of the CLAMS was excellent (a = 0.933) for the PwMS and a significant difference was found between PwMS and HCs for the total CLAMS score. Statistical analyses showed a significant positive correlation between the CLAMS and the other questionnaires (SMS, BDI, and SAQOL-39) and a statistically significant negative correlation between the CLAMS and the three subtests of the BICAMS (Symbol Digit Modalities Test, Greek Verbal Learning Test-II, and Brief Visuospatial Memory Test-Revised). There was no correlation between the CLAMS and participants' age, disease duration, and disease type.
The Greek version of the CLAMS is a valid self-reported questionnaire for the evaluation of language and communication symptoms in PwMS.
本研究旨在将多发性硬化症患者沟通与语言评估问卷（CLAMS）翻译成希腊语并进行验证。
106例多发性硬化症患者（PwMS）和51名健康对照者（HCs）参与了本研究。我们使用多发性硬化症简易国际认知评估量表（BICAMS）评估患者的认知能力。所有PwMS患者均完成了CLAMS问卷以及另外三份问卷（多发性硬化症言语病理学专用问卷，SMS；中风与失语生活质量量表-39，SAQOL-39；贝克抑郁量表快速筛查版，BDI-FS），所有HCs填写了CLAMS问卷。
CLAMS问卷在PwMS患者中的内部一致性极佳（α = 0.933），PwMS患者与HCs在CLAMS总分上存在显著差异。统计分析表明，CLAMS与其他问卷（SMS、BDI和SAQOL-39）之间存在显著正相关，与BICAMS的三个子测试（符号数字模态测试、希腊语言语学习测试-II和简易视觉空间记忆测试-修订版）之间存在显著负相关。CLAMS与参与者的年龄、病程和疾病类型之间无相关性。
CLAMS希腊语版本是一种有效的自评问卷，可用于评估PwMS患者的语言和沟通症状。
