Wang Jin-Hui, Luan Fei, He Xiang-Dong, Wang Yong, Li Mao-Xing
Department of Pharmacy, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China.
Department of Pharmacy, Xi'an Weiyang District Hospital of Chinese Medicine, Xi'an 710015, Shanxi, China.
J Tradit Complement Med. 2017 May 11;8(1):24-38. doi: 10.1016/j.jtcme.2017.04.001. eCollection 2018 Jan.
is a genus of . 500 species in the family Lamiaceae and widely distributed throughout the whole world. Up to now, many species of this genus have been described in various indigenous systems of medicine and are used in preparation of folklore medicines for the treatment of various life-threatening diseases, and more than eleven species of the genus have been very well studied for their chemical constituents and biological activities, and 283 compounds, including monoterpene and its derivatives, sesquiterpene, diterpenoids, triterpenoids, flavonoid and flavonoid glycosides, phenylethanoid glycosides, steroids and steroid glycosides, cyclohexylethanoids, anthraquinones, cyanogenic glycosides, and others have been isolated and identified. Pharmacological studies have shown that these compounds and extracts from the genus have extensive activities, such as anti-inflammatory and anti-nociceptive, anti-oxidant, anti-hypertensive, anticancer, antimicrobial, anti-diarrheal, hepatoprotective, hypoglycemic and hypolipidemic, memory enhancing and neuroprotective, and other activities. In this review, we attempt to highlight over phytochemical progress and list the phytoconstituents isolated from the genus reported so far. The biological activities of this genus are also covered.
是唇形科的一个属。该科有500个物种，广泛分布于全世界。到目前为止，该属的许多物种已在各种本土医学体系中被描述，并被用于制备民间药物以治疗各种危及生命的疾病。该属已有超过11个物种的化学成分和生物活性得到了深入研究，已分离并鉴定出283种化合物，包括单萜及其衍生物、倍半萜、二萜、三萜、黄酮类和黄酮苷、苯乙醇苷、甾体和甾体苷、环己基乙醇类、蒽醌、氰苷等。药理学研究表明，这些化合物以及该属植物的提取物具有广泛的活性，如抗炎、抗伤害感受、抗氧化、抗高血压、抗癌、抗菌、止泻、保肝、降血糖和降血脂、增强记忆和神经保护等活性。在本综述中，我们试图突出该属植物的化学进展，并列出迄今为止报道的从该属植物中分离出的植物成分。同时也涵盖了该属植物的生物活性。
