Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4AX, UK.
Curr Opin Microbiol. 2018 Jun;43:84-91. doi: 10.1016/j.mib.2017.12.005. Epub 2018 Jan 12.
Bacterial cell division takes place almost entirely below the diffraction limit of light microscopy, making super-resolution microscopy ideally suited to interrogating this process. I review how super-resolution microscopy has advanced our understanding of bacterial cell division. I discuss the mechanistic implications of these findings, propose physical models for cell division compatible with recent data, and discuss key outstanding questions and future research directions.
细菌细胞分裂几乎完全发生在光显微镜的衍射极限以下，因此超分辨率显微镜非常适合研究这个过程。我回顾了超分辨率显微镜如何促进我们对细菌细胞分裂的理解。我讨论了这些发现的机械学意义，提出了与最新数据兼容的细胞分裂物理模型，并讨论了关键的未解决问题和未来的研究方向。
