Shin Ji-Hyeon, Roh Daeyoung, Lee Dong-Hee, Kim Soo Whan, Kim Sung Won, Cho Jin Hee, Kim Byung-Guk, Kim Boo-Young
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Psychiatry, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon-si, Gangwon-do, Republic of Korea.
PLoS One. 2018 Jan 11;13(1):e0191115. doi: 10.1371/journal.pone.0191115. eCollection 2018.
Allergic rhinitis (AR) and rhinosinusitis (RS) negatively impact psychological well-being and health-related quality of life (HRQoL). However, few population-based studies have investigated the effects of these conditions on mental health and HRQoL.
To explore independent associations of AR and/or RS with mental health and HRQoL using data from the 2013-2015 Korea National Health and Nutrition Examination Survey (KNHANES).
The KNHANES is a nationwide cross-sectional survey of the non-institutionalized population of Korea. A total of 15,441 adults completed the clinical examination and the health questionnaire. We divided all participants into four groups: AR-/RS-, AR-/RS+, AR+/RS-, and AR+/RS+. Logistic regression analyses were performed after adjustment for sociodemographic characteristics, general health behaviors, and other comorbidities.
The AR+/RS+ group contained the highest proportion of subjects with perceived stress and depressed mood. Subjects with AR+/RS+ also had more frequent problems in terms of pain/discomfort and anxiety/depression. After adjusting for all confounders, the odds ratios (ORs) were 2.96 (p = 0.009) for depressed mood and 3.17 (p = 0.013) for suicidal ideation in the AR+/RS+ group compared with in the AR-/RS- group. The AR+/RS- group reported more perceived stress (OR, 1.56, p = 0.003) and depression (OR, 1.72, p = 0.024) compared with the AR-/RS- group. In terms of the ORs for HRQoL, the AR+/RS+ group reported more problems in terms of self-care (OR, 3.73, p = 0.038) and more pain/discomfort (OR 2.19, p = 0.006) compared with the AR-/RS- group.
In the Korean population, AR and RS exerted a synergistic negative impact on mental health and HRQoL, especially suicidal ideation. Most patients seek help from clinicians for impaired HRQoL. Therefore, clinicians should consider the underlying mental health and HRQoL of patients with AR and/or RS, as these may be impaired by their conditions.
变应性鼻炎（AR）和鼻-鼻窦炎（RS）对心理健康和健康相关生活质量（HRQoL）产生负面影响。然而，基于人群的研究很少调查这些疾病对心理健康和HRQoL的影响。
利用2013 - 2015年韩国国家健康与营养检查调查（KNHANES）的数据，探讨AR和/或RS与心理健康和HRQoL的独立关联。
KNHANES是一项针对韩国非机构化人群的全国性横断面调查。共有15441名成年人完成了临床检查和健康问卷。我们将所有参与者分为四组：AR-/RS-、AR-/RS+、AR+/RS-和AR+/RS+。在对社会人口学特征、一般健康行为和其他合并症进行调整后，进行逻辑回归分析。
AR+/RS+组中感知压力和情绪低落的受试者比例最高。AR+/RS+组的受试者在疼痛/不适和焦虑/抑郁方面也有更频繁的问题。在对所有混杂因素进行调整后，与AR-/RS-组相比，AR+/RS+组情绪低落的优势比（OR）为2.96（p = 0.009），自杀意念的OR为3.17（p = 0.013）。与AR-/RS-组相比，AR+/RS-组报告了更多的感知压力（OR，1.56，p = 0.003）和抑郁（OR，1.72，p = 0.024）。就HRQoL的OR而言，与AR-/RS-组相比，AR+/RS+组在自我护理方面报告了更多问题（OR，3.73，p = 0.038）和更多疼痛/不适（OR 2.19，p = 0.006）。
在韩国人群中，AR和RS对心理健康和HRQoL产生协同负面影响，尤其是自杀意念。大多数患者因HRQoL受损而寻求临床医生的帮助。因此，临床医生应考虑AR和/或RS患者潜在的心理健康和HRQoL，因为这些可能会因他们的病情而受损。
