来自森林地区的牛的血浆病毒组揭示了多样化的小型环状 ssDNA 病毒基因组。
Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes.
机构信息
Department of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Department of Swine Infectious Disease, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China.
出版信息
Virol J. 2018 Jan 15;15(1):11. doi: 10.1186/s12985-018-0923-9.
BACKGROUND
Free-range cattle are common in the Northeast China area, which have close contact with farmers and may carry virus threatening to cattle and farmers.
METHODS
Using viral metagenomics we analyzed the virome in plasma samples collected from 80 cattle from the forested region of Northeast China.
RESULTS
The virome of cattle plasma is composed of the viruses belonging to the families including Parvoviridae, Papillomaviridae, Picobirnaviridae, and divergent viral genomes showing sequence similarity to circular Rep-encoding single stranded (CRESS) DNA viruses. Five such CRESS-DNA genomes were full characterized, with Rep sequences related to circovirus and gemycircularvirus. Three bovine parvoviruses belonging to two different genera were also characterized.
CONCLUSION
The virome in plasma samples of cattle from the forested region of Northeast China was revealed, which further characterized the diversity of viruses in cattle plasma.
背景
在中国东北地区，散养牛很常见，它们与农民密切接触，可能携带威胁牛和农民的病毒。
方法
我们使用病毒宏基因组学分析了从中国东北地区林区采集的 80 头牛的血浆样本中的病毒组。
结果
牛血浆的病毒组由属于细小病毒科、乳头瘤病毒科、微小 RNA 病毒科的病毒以及与圆形 Rep 编码单链 (CRESS) DNA 病毒具有序列相似性的离散病毒基因组组成。其中五个 CRESS-DNA 基因组被完全表征，其 Rep 序列与圆环病毒和 gemycircularvirus 相关。还鉴定了属于两个不同属的三种牛细小病毒。
结论
揭示了来自中国东北地区林区的牛血浆样本中的病毒组，进一步描述了牛血浆中病毒的多样性。
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