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(A. 圣伊莱尔) 贝利的化学与生物学见解:具有多功能特性的生物活性化合物来源。

Chemical and Biological insights of (A. St.-Hil.) Baill.: a source of bioactive compounds with multifunctional properties.

作者信息

Fidelis Queli Cristina, Faraone Immacolata, Russo Daniela, Aragão Catunda-Jr Francisco Eduardo, Vignola Lisiana, de Carvalho Mario Geraldo, de Tommasi Nunziatina, Milella Luigi

机构信息

a Departamento de Química , Instituto de Ciências Exatas, Universidade Federal Rural do Rio de Janeiro , Seropédica , RJ , Brasil.

b Dipartimento di Scienze , Università degli Studi della Basilicata , Potenza , Italy.

出版信息

Nat Prod Res. 2019 May;33(10):1500-1503. doi: 10.1080/14786419.2017.1419227. Epub 2018 Jan 16.

DOI:10.1080/14786419.2017.1419227
PMID:29338358
Abstract

The study aimed to evaluate antioxidant, anticholinesterase and antidiabetic properties of (A. St.-Hil.) Baill. The inflorescence methanol extract and the ethyl acetate fraction of leaves and stems reported the highest Relative Antioxidant Capacity Index (RACI), whereas the dichloromethane fraction of leaves was the best inhibitor of -amylase and -glucosidase. T-3--methyl-resveratrol-2---glucoside, lithospermoside, 2,5-dimethoxy--benzoquinone, lup-20(30)-ene-3β,28-diol, 7--methylgenistein, apigenin and luteolin and amentoflavone were isolated from . Resveratrol derivative was isolated for the first time in Ochnaceae family. Luteolin, followed by apigenin, reported the highest Relative Antioxidant Capacity Index and they were also the best inhibitors of α-glucosidase enzyme.

摘要

该研究旨在评估(A. St.-Hil.)Baill.的抗氧化、抗胆碱酯酶和抗糖尿病特性。花序甲醇提取物以及叶和茎的乙酸乙酯部分的相对抗氧化能力指数(RACI)最高,而叶的二氯甲烷部分是α-淀粉酶和α-葡萄糖苷酶的最佳抑制剂。从该植物中分离出了T-3'-甲基白藜芦醇-2''-葡萄糖苷、紫草酸苷、2,5-二甲氧基-对-苯醌、羽扇-20(30)-烯-3β,28-二醇、7-甲氧基染料木黄酮、芹菜素、木犀草素和穗花杉双黄酮。白藜芦醇衍生物首次在金莲木科中被分离出来。木犀草素的相对抗氧化能力指数最高,其次是芹菜素,它们也是α-葡萄糖苷酶的最佳抑制剂。

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