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来自缅甸的恶性疟原虫分离株对氯喹、奎宁和甲氟喹的体外敏感性。

In vitro sensitivity of Plasmodium falciparum isolates from Burma to chloroquine quinine and mefloquine.

作者信息

Lwin M, Zaw M

出版信息

Southeast Asian J Trop Med Public Health. 1985 Sep;16(3):453-8.

PMID:2937157
Abstract

The in vitro sensitivity of 26 isolates of Plasmodium falciparum from Rangoon and Tharrawaddy areas in Burma were studied on chloroquine, mefloquine and quinine. The results indicated that the parasites were highly resistant to chloroquine but sensitive to mefloquine and quinine. The existence of correlation of sensitivity to mefloquine and quinine was detected and discussed. No correlation between the parasite sensitivity to chloroquine and mefloquine and or chloroquine and quinine was detected.

摘要

对来自缅甸仰光和德耶瓦底地区的26株恶性疟原虫分离株进行了氯喹、甲氟喹和奎宁的体外敏感性研究。结果表明,这些疟原虫对氯喹高度耐药,但对甲氟喹和奎宁敏感。检测并讨论了对甲氟喹和奎宁敏感性之间的相关性。未检测到疟原虫对氯喹与甲氟喹和/或氯喹与奎宁之间的相关性。

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