Saito Hidekazu, Jwa Seung Chik, Kuwahara Akira, Saito Kazuki, Ishikawa Tomonori, Ishihara Osamu, Kugu Koji, Sawa Rintaro, Banno Kouji, Irahara Minoru
Division of Reproductive Medicine Center of Maternal-Fetal, Neonatal, and Reproductive Medicine National Center for Child Health and Development Tokyo Japan.
Department of Obstetrics and Gynecology Saitama Medical University Saitama Japan.
Reprod Med Biol. 2017 Nov 29;17(1):20-28. doi: 10.1002/rmb2.12074. eCollection 2018 Jan.
The Japan Society of Obstetrics and Gynecology (JSOG) implemented an assisted reproductive technology (ART) registry system in 1986. Here are reported the characteristics and treatment outcomes of ART cycles that were registered in 2015.
JSOG has requested all participating ART facilities to register cycle-specific information for all ART cycles since 2007. A descriptive analysis was performed by using the registry database for 2015.
In total, 424 151 cycles and 51 001 neonates (1 in 19.7 neonates born in Japan) were registered in 2015. The patients' mean age was 38.2 years (standard deviation = 4.5). Among the fresh cycles, 94 158 of 244 718 (38.5%) egg retrieval cycles were cycles with freeze-all embryos or oocytes, while fresh embryo transfer (ET) was performed in 70 254 cycles, signaling a decrease from 2014. There were 169 898 frozen-thawed ET cycles, resulting in 56 355 pregnancies and 40 599 neonates. Single ET was performed at a rate of 79.7% for fresh and 81.8% for frozen cycles and the singleton pregnancy/live birth rates were 96.9%/96.5% and 96.8%/96.4% for the respective cycles.
The total ART cycles and live births resulting from ART has been increasing in Japan. Single ET was performed at a rate of almost 80% and ET cycles have shifted from fresh to frozen cycles.
日本妇产科学会(JSOG)于1986年实施了辅助生殖技术(ART)登记系统。本文报告了2015年登记的ART周期的特征和治疗结果。
自2007年以来,JSOG要求所有参与的ART机构登记所有ART周期的特定周期信息。使用2015年的登记数据库进行描述性分析。
2015年共登记了424151个周期和51001名新生儿(占日本出生新生儿的1/19.7)。患者的平均年龄为38.2岁(标准差=4.5)。在新鲜周期中,244718个取卵周期中有94158个(38.5%)是冷冻所有胚胎或卵母细胞的周期,而70254个周期进行了新鲜胚胎移植(ET),较2014年有所下降。有169898个冻融ET周期,导致56355例妊娠和40599名新生儿。新鲜周期单胚胎移植率为79.7%,冷冻周期为81.8%,相应周期的单胎妊娠/活产率分别为96.9%/96.5%和96.8%/96.4%。
日本ART的总周期数和ART带来的活产数一直在增加。单胚胎移植率近80%,胚胎移植周期已从新鲜周期转向冷冻周期。