Mills Robert Coleman
Duke Cancer Institute, Department of Medicine, Durham, NC, USA.
Breast Cancer (Auckl). 2017 Nov 24;11:1178223417743976. doi: 10.1177/1178223417743976. eCollection 2017.
Exercise may help positively improve inflammatory marker levels, therefore promoting better outcomes in breast cancer survivors. This narrative review is intended to provide an overview between inflammation and breast cancer, in addition to the effects exercise may have on common inflammatory markers that have been examined in both healthy populations and breast cancer survivors throughout the literature. The inconsistencies and gaps in the literature addressed may be important for future research to further understand the relationship between exercise and inflammation, as well as the underlying biological mechanisms that are responsible for these changes. For the purpose of organization, this review is structured into the following sections: (1) Breast Cancer Facts, Treatment-Related Side Effects, and General Exercise Benefits; (2) Effects of Exercise on Markers of Inflammation in Cancer-Free Populations; (3) Cancer and Markers of Inflammation; (4) Effects of Exercise on Markers of Inflammation in Breast Cancer Survivors; and (5) Conclusions.
运动可能有助于积极改善炎症标志物水平，从而使乳腺癌幸存者获得更好的预后。本叙述性综述旨在概述炎症与乳腺癌之间的关系，以及运动对文献中在健康人群和乳腺癌幸存者中均已检测的常见炎症标志物可能产生的影响。文献中存在的不一致和空白对于未来研究进一步理解运动与炎症之间的关系以及导致这些变化的潜在生物学机制可能很重要。为便于组织，本综述分为以下几个部分：（1）乳腺癌事实、治疗相关副作用及运动的总体益处；（2）运动对无癌人群炎症标志物的影响；（3）癌症与炎症标志物；（4）运动对乳腺癌幸存者炎症标志物的影响；（5）结论。
