Maldonado Ramiro S, Mettu Pradeep, El-Dairi Mays, Bhatti M Tariq
Department of Ophthalmology (RSM, PM, ME-D, MTB), Duke University Eye Center; and Department of Neurology (MTB), Duke University School of Medicine, Durham, NC.
Neurol Clin Pract. 2015 Oct;5(5):460-469. doi: 10.1212/CPJ.0000000000000187.
Optical coherence tomography (OCT) has become an increasingly popular tool in various disciplines of medicine, particularly ophthalmology and neurology. It is an imaging technology that has revolutionized the practice of ophthalmology by providing anatomic detail of pathologic changes in the retina and optic nerve. OCT is routinely used as an ancillary test that can aid in the diagnosis and monitoring of neuro-ophthalmic diseases such as papilledema, optic neuritis, and neuroretinitis. OCT measurements have also been shown to predict visual prognosis in compressive optic neuropathies. Changes in OCT measurements have been used to study the course of particular neurologic diseases such as multiple sclerosis, suggesting that the data obtained may be useful as a biomarker in diagnosing and treating neurodegenerative disease. We present an up-to-date review of the OCT findings in several diseases of neurologic interest and provide clinical examples pertinent to the general neurologist.
光学相干断层扫描（OCT）在医学的各个学科中已成为越来越受欢迎的工具，尤其是在眼科和神经科。它是一种成像技术，通过提供视网膜和视神经病理变化的解剖细节，彻底改变了眼科的诊疗方式。OCT通常用作辅助检查，有助于诊断和监测视乳头水肿、视神经炎和神经视网膜炎等神经眼科疾病。OCT测量还被证明可预测压迫性视神经病变的视觉预后。OCT测量的变化已被用于研究特定神经系统疾病（如多发性硬化症）的病程，这表明所获得的数据可能作为诊断和治疗神经退行性疾病的生物标志物有用。我们对几种神经相关疾病的OCT检查结果进行了最新综述，并提供了与普通神经科医生相关的临床实例。
