膜的脱离对于 COG 复合物的功能并非必需。
Membrane detachment is not essential for COG complex function.
机构信息
College of Medicine, Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205.
出版信息
Mol Biol Cell. 2018 Apr 15;29(8):964-974. doi: 10.1091/mbc.E17-11-0694. Epub 2018 Mar 30.
Abstract
COG is a multisubunit vesicle tethering complex in the Golgi. We demonstrate that both COG subcomplexes can be permanently attached to Golgi membranes and that major COG functions do not require cycling between the membrane and cytosol.
摘要
COG 是高尔基体中的一个多亚基囊泡连接复合物。我们证明，两个 COG 亚基复合物都可以永久附着在高尔基体膜上，并且 COG 的主要功能不需要在膜和细胞质之间循环。
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