Guo Peng, Huang Jing, Zhao Yaping, Martin Charles R, Zare Richard N, Moses Marsha A
Vascular Biology Program, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Department of Surgery, Harvard Medical School and Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Small. 2018 May;14(18):e1703493. doi: 10.1002/smll.201703493. Epub 2018 Feb 22.
Template synthesis represents an important class of nanofabrication methods. Herein, recent advances in nanomaterial preparation by extrusion through nanoporous membranes that preserve the template membrane without sacrificing it, which is termed as "non-sacrificing template synthesis," are reviewed. First, the types of nanoporous membranes used in nanoporous membrane extrusion applications are introduced. Next, four common nanoporous membrane extrusion strategies: vesicle extrusion, membrane emulsification, precipitation extrusion, and biological membrane extrusion, are examined. These methods have been utilized to prepare a wide range of nanomaterials, including liposomes, emulsions, nanoparticles, nanofibers, and nanotubes. The principle and historical context of each specific technology are discussed, presenting prominent examples and evaluating their positive and negative features. Finally, the current challenges and future opportunities of nanoporous membrane extrusion methods are discussed.
模板合成是一类重要的纳米制造方法。本文综述了通过纳米多孔膜挤出制备纳米材料的最新进展,该方法在不牺牲模板膜的情况下保留模板膜,即所谓的“非牺牲模板合成”。首先,介绍了纳米多孔膜挤出应用中使用的纳米多孔膜类型。接下来,研究了四种常见的纳米多孔膜挤出策略:囊泡挤出、膜乳化、沉淀挤出和生物膜挤出。这些方法已被用于制备各种纳米材料,包括脂质体、乳液、纳米颗粒、纳米纤维和纳米管。讨论了每种特定技术的原理和历史背景,给出了突出的例子并评估了它们的优缺点。最后,讨论了纳米多孔膜挤出方法当前面临的挑战和未来机遇。